{"id":"W2012868945","doi":"10.1016/j.atherosclerosis.2013.07.056","title":"Lipid lowering in healthy volunteers treated with multiple doses of MGL-3196, a liver-targeted thyroid hormone receptor-β agonist","year":2013,"lang":"en","type":"article","venue":"Atherosclerosis","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":160,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Agonist; Internal medicine; Endocrinology; Medicine; Thyroid hormone receptor; Thyroid; Receptor; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004030567,0.0005252531,0.001347554,0.0002979303,0.0004482923,0.0003631846,0.0002256503,0.0009089819,0.001924784],"category_scores_gemma":[0.0007596825,0.0003726016,0.0006827049,0.000246495,0.0002444709,0.0003182088,0.0001919969,0.000936816,0.0003056615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003034145,"about_ca_system_score_gemma":0.0003265083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002431073,"about_ca_topic_score_gemma":0.004392653,"domain_scores_codex":[0.9997454,0.00007868117,0.00002599199,0.00005462272,0.00003838039,0.00005688819],"domain_scores_gemma":[0.9997573,0.00004660303,0.00004773431,0.00001839013,0.0000276884,0.0001021757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7315106,0.01252229,0.09914742,0.0004489002,0.002744776,0.002316353,0.0004318506,0.0004443884,0.08863749,0.0001000722,0.002127427,0.05956838],"study_design_scores_gemma":[0.04275717,0.2343217,0.6959497,0.00009365329,0.005161742,0.001738429,0.0005851692,0.002496146,0.01316047,0.0002885197,0.003325693,0.0001216513],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973449,0.001060895,0.0001432198,0.000142772,0.00006841321,0.00007695411,0.0002306226,0.00003821279,0.0008941271],"genre_scores_gemma":[0.9983414,0.0003270904,0.0001749242,0.0001965188,0.00005167603,0.00004373759,0.0001967421,0.000004846153,0.000663072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002431073,"threshold_uncertainty_score":0.00643903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01368847017811,"score_gpt":0.2233280165257992,"score_spread":0.2096395463476892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}