{"id":"W2012880829","doi":"10.1111/j.1750-3639.2003.tb00484.x","title":"TRAIL Triggers Apoptosis in Human Malignant Glioma Cells Through Extrinsic and Intrinsic Pathways","year":2003,"lang":"en","type":"article","venue":"Brain Pathology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute","keywords":"Apoptosis; Glioma; Cancer research; Camptothecin; Caspase; Tumor necrosis factor alpha; Programmed cell death; Cisplatin; Etoposide; Cell culture; Biology; Intrinsic apoptosis; Chemistry; Cell biology; Immunology; Chemotherapy; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008810358,0.0002524891,0.0001672662,0.00018577,0.0001406151,0.0001884022,0.00008026891,0.0001251758,0.0009265256],"category_scores_gemma":[0.0001000848,0.00006712142,0.0001377598,0.0001947431,0.0001019672,0.0001139856,0.0001462051,0.0002356134,0.000434265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002424685,"about_ca_system_score_gemma":0.00018885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006415628,"about_ca_topic_score_gemma":0.001006695,"domain_scores_codex":[0.9998858,0.0000196351,0.000009787201,0.00001088804,0.00004188957,0.00003206994],"domain_scores_gemma":[0.9999632,0.00000481395,0.000009264109,0.000005815505,0.000008397865,0.000008511373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003841001,0.00006671025,0.001017467,0.000118521,0.00001107436,0.000308952,0.00006154111,0.00007237788,0.9899737,0.0002849999,0.0002157259,0.007484837],"study_design_scores_gemma":[0.00006419168,0.0008595192,0.009650716,0.00001006615,0.00002711217,0.001558679,0.00004966843,0.0003518265,0.9798263,0.000119751,0.007477175,0.000004808567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858854,0.0075284,0.002251017,0.0001435329,0.00003178131,0.00004883251,0.0005548609,0.00007153367,0.003484771],"genre_scores_gemma":[0.9910745,0.004185501,0.001389103,0.00006254998,0.00002200188,0.00003622612,0.0008475487,0.000008008635,0.002374646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009265256,"threshold_uncertainty_score":0.003099561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01489154239238956,"score_gpt":0.2356114533547329,"score_spread":0.2207199109623433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}