{"id":"W2012888336","doi":"10.1016/j.neuron.2008.06.027","title":"FMRP Acts as a Key Messenger for Dopamine Modulation in the Forebrain","year":2008,"lang":"en","type":"article","venue":"Neuron","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":192,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health; Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Forebrain; Neuroscience; Dopamine; Second messenger system; Key (lock); Modulation (music); Psychology; Communication; Biology; Cell biology; Signal transduction; Central nervous system; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003256179,0.000144336,0.0001332554,0.00017399,0.0003639276,0.00004117419,0.0005840028,0.00004831842,0.00003452313],"category_scores_gemma":[0.001473305,0.0001050276,0.00006330779,0.0006375293,0.0002510881,0.0003146151,0.00007548028,0.0003243193,0.00009121431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001638119,"about_ca_system_score_gemma":0.00006916211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005952282,"about_ca_topic_score_gemma":0.000004369526,"domain_scores_codex":[0.997877,0.0003989595,0.000197289,0.0005581959,0.0004663637,0.0005021686],"domain_scores_gemma":[0.9984212,0.001118675,0.00005626576,0.0003047016,0.00002699048,0.00007220488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000113087,0.0001318652,0.000311285,0.000007678245,2.832037e-7,0.0002974521,0.0002946629,0.00008731442,0.9963113,0.0008120604,0.001191871,0.0004411629],"study_design_scores_gemma":[0.001477887,0.0008729887,0.02558096,0.000005411869,0.00000463796,0.0005123012,0.00002200531,0.009123669,0.9319292,0.000657679,0.0296145,0.0001987177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922912,0.000007065442,0.00002067849,0.004826585,0.0003218843,0.0008706824,0.00000588376,0.00004877232,0.001607215],"genre_scores_gemma":[0.9898755,0.00009342091,0.000009936803,0.008738343,0.0001076433,0.0001448843,7.890663e-7,0.00002262499,0.001006877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06438203,"threshold_uncertainty_score":0.42829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1028543845994961,"score_gpt":0.3633196989503438,"score_spread":0.2604653143508477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}