{"id":"W2012888336","doi":"10.1016/j.neuron.2008.06.027","title":"FMRP Acts as a Key Messenger for Dopamine Modulation in the Forebrain","year":2008,"lang":"en","type":"article","venue":"Neuron","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":192,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health; Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Forebrain; Neuroscience; Dopamine; Second messenger system; Key (lock); Modulation (music); Psychology; Communication; Biology; Cell biology; Signal transduction; Central nervous system; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001094889,0.0003480469,0.0002794703,0.0002439754,0.0003663315,0.000475694,0.0002239216,0.0005025194,0.001101654],"category_scores_gemma":[0.0001592488,0.0001132148,0.0002110224,0.0001123633,0.0004090407,0.0004988936,0.0002532208,0.0006487865,0.0002470597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000624113,"about_ca_system_score_gemma":0.0001927377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0012104,"about_ca_topic_score_gemma":0.00131168,"domain_scores_codex":[0.9999149,0.00001454739,0.000004870335,0.00002236202,0.00001695664,0.000026349],"domain_scores_gemma":[0.9999456,0.00000860597,0.00001035101,0.000003596751,0.00001016904,0.00002163967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004157228,0.00001428683,0.0003473133,0.0001052758,0.00001418062,0.0005764943,0.00004157218,0.00006929665,0.987615,0.001314683,0.0002010155,0.009285191],"study_design_scores_gemma":[0.00006627849,0.001002359,0.05557794,0.00008082874,0.00009747484,0.002483318,0.0002335367,0.001034546,0.9280418,0.002452648,0.008896363,0.00003290989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9526297,0.0214162,0.009207751,0.001096206,0.0003115151,0.00003397538,0.0004964538,0.0001061305,0.01470203],"genre_scores_gemma":[0.989155,0.003694833,0.003168207,0.0001349992,0.0001238547,0.00001305106,0.0001330043,0.00001418289,0.003562912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0012104,"threshold_uncertainty_score":0.004528344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1028543845994961,"score_gpt":0.3633196989503438,"score_spread":0.2604653143508477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}