{"id":"W2012891747","doi":"10.1089/dna.2006.25.116","title":"Interaction of Antioxidant Flavonoids with tRNA: Intercalation or External Binding and Comparison with Flavonoid-DNA Adducts","year":2006,"lang":"en","type":"article","venue":"DNA and Cell Biology","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières; Innovation and Economic Development Trois Rivières","funders":"Natural Sciences and Engineering Research Council of Canada; Kentucky Agricultural Experiment Station","keywords":"Intercalation (chemistry); Binding constant; DNA; Transfer RNA; Duplex (building); Stereochemistry; Kaempferol; Adduct; Flavonoid; RNA; Binding site; Chemistry; Antioxidant; Crystallography; Biology; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005696847,0.0001518621,0.0001956441,0.00003800697,0.00005116432,0.00001474248,0.00006095466,0.0001405526,0.00001565689],"category_scores_gemma":[0.000004665647,0.0001029093,0.00002123494,0.00004455546,0.0001827305,0.000007923417,0.0000463282,0.0000809771,0.00000121279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007302296,"about_ca_system_score_gemma":0.00002182051,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003840539,"about_ca_topic_score_gemma":0.00005365311,"domain_scores_codex":[0.999272,0.00002882084,0.0002010624,0.0002943656,0.0000432527,0.0001605169],"domain_scores_gemma":[0.9996224,0.00001400287,0.0001529236,0.0001254704,0.00004051907,0.00004470149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006601734,0.00006381344,0.02377033,0.00004537971,0.0000226346,0.000002895506,0.00004050109,0.00000494598,0.9734492,0.0000257937,0.00009248218,0.001821864],"study_design_scores_gemma":[0.0009078521,0.0009906748,0.005219523,0.00003711402,0.00003266256,0.00004450173,0.0002306541,0.00007989113,0.9902103,0.00001554629,0.002070362,0.0001609505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971884,0.0003192341,0.0009066346,0.00002461265,0.00005570952,0.00007789803,0.00001181242,0.00000859955,0.001407055],"genre_scores_gemma":[0.9985979,0.0001091565,0.0006115939,0.00002440003,0.0001170352,0.000005084445,0.0001062617,0.00001310729,0.0004154608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01855081,"threshold_uncertainty_score":0.4196519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006784370787845048,"score_gpt":0.2303000727148254,"score_spread":0.2235157019269804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}