{"id":"W2012933881","doi":"10.1016/j.cyto.2013.03.027","title":"Parainflammation associated with advanced glycation endproduct stimulation of RPE in vitro: Implications for age-related degenerative diseases of the eye","year":2013,"lang":"en","type":"article","venue":"Cytokine","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Canada; University of Saskatchewan; University of British Columbia; Western University","funders":"Canadian Institutes of Health Research","keywords":"Drusen; Inflammation; Macular degeneration; Bruch's membrane; Lipofuscin; Immunology; Glycation; Biology; Retinal pigment epithelium; Medicine; Retina; Internal medicine; Receptor; Neuroscience; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001090639,0.00008797896,0.000136997,0.00007422981,0.00004881231,0.000005392519,0.0001237757,0.00005695498,0.000006830886],"category_scores_gemma":[0.0007296935,0.00006643905,0.00004805134,0.0005249264,0.0001056562,0.00001774889,0.00002918099,0.0000442553,4.45475e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003206201,"about_ca_system_score_gemma":0.00007554454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009210789,"about_ca_topic_score_gemma":0.00002218284,"domain_scores_codex":[0.9991892,0.00007849256,0.0002755515,0.00023372,0.0001001689,0.0001228818],"domain_scores_gemma":[0.9987908,0.00004159601,0.0002626595,0.0003586752,0.0005217345,0.00002451474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001313059,0.00008113915,0.009013827,0.00001565308,0.00007352695,1.889942e-8,0.0000620806,0.02984254,0.9568445,0.0002995529,0.00002987429,0.003605987],"study_design_scores_gemma":[0.0005769935,0.00008343964,0.4217139,0.000009033942,0.00003111816,1.180919e-7,0.00001335209,0.0006791874,0.5761036,0.0006259969,0.0001041038,0.0000590848],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990566,0.0001833511,0.006859849,0.0008132254,0.00002498656,0.001343646,0.0001506297,0.000007516293,0.0000508509],"genre_scores_gemma":[0.9962323,0.00001600658,0.001267925,0.00001401891,0.00002364842,0.0002909017,0.00180601,0.00001255259,0.0003365994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4127001,"threshold_uncertainty_score":0.2709306,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01255289751106356,"score_gpt":0.2887407743409136,"score_spread":0.27618787682985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}