{"id":"W2012936624","doi":"10.1161/01.cir.102.7.728","title":"Dose-Finding, Safety, and Tolerability Study of an Oral Platelet Glycoprotein IIb/IIIa Inhibitor, Lotrafiban, in Patients With Coronary or Cerebral Atherosclerotic Disease","year":2000,"lang":"en","type":"article","venue":"Circulation","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Tolerability; Aspirin; Placebo; Internal medicine; Platelet; Clinical endpoint; Platelet aggregation inhibitor; Adverse effect; Dosing; Platelet activation; Gastroenterology; Randomized controlled trial; Anesthesia; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002245557,0.0008562196,0.001870998,0.0003263857,0.0002814718,0.0006299904,0.0006372246,0.001100011,0.002341627],"category_scores_gemma":[0.003443542,0.0004451308,0.001316768,0.0003417416,0.0008821986,0.0006050256,0.0002618074,0.001800109,0.0004110717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004444865,"about_ca_system_score_gemma":0.0007161372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000349976,"about_ca_topic_score_gemma":0.0005978298,"domain_scores_codex":[0.9985201,0.0009899064,0.0001017018,0.0001537425,0.0001540547,0.00008062127],"domain_scores_gemma":[0.9970632,0.00097848,0.0007506096,0.000279852,0.0002079691,0.0007198694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8631198,0.03112429,0.01532206,0.0008729695,0.003164914,0.0003114147,0.0003012405,0.001108216,0.02423995,0.0001318887,0.001157684,0.05914549],"study_design_scores_gemma":[0.4197604,0.54002,0.03499274,0.0000346671,0.001006613,0.0002956356,0.00004012107,0.0007672029,0.001886115,0.00009605711,0.00106952,0.00003091152],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957542,0.001788656,0.0004460422,0.0002543229,0.00006723661,0.0005763939,0.0002691802,0.00003301541,0.0008109587],"genre_scores_gemma":[0.9963095,0.0007319784,0.0008012288,0.0006239529,0.0002584838,0.0004118162,0.0004016811,0.000008558498,0.0004528983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002341627,"threshold_uncertainty_score":0.01187581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01703083443064514,"score_gpt":0.254223720538179,"score_spread":0.2371928861075338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}