{"id":"W2012980382","doi":"10.1021/tx400434b","title":"Epimers of Azaspiracids: Isolation, Structural Elucidation, Relative LC-MS Response, and <i>in Vitro</i> Toxicity of 37-<i>epi</i>-Azaspiracid-1","year":2014,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Marine Toxins and Detection Methods","field":"Environmental Science","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Epimer; Chemistry; Stereochemistry; Stereoisomerism; Nuclear magnetic resonance spectroscopy; EC50; In vitro; Chromatography; Biochemistry; Molecule; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001826032,0.0006386194,0.0002819658,0.0003743691,0.000187455,0.0002433544,0.0002449688,0.0002899399,0.0007710753],"category_scores_gemma":[0.0002703745,0.0001668897,0.0002880743,0.0003185627,0.0002013191,0.000191457,0.0001523125,0.0004076984,0.0003266942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004022344,"about_ca_system_score_gemma":0.0003168384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001804107,"about_ca_topic_score_gemma":0.001739488,"domain_scores_codex":[0.9998062,0.00002925807,0.0000159683,0.00004341375,0.00007612661,0.00002894987],"domain_scores_gemma":[0.9998719,0.00001657023,0.00002800605,0.00001060676,0.00004927634,0.00002376659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009261883,0.00001160257,0.000222923,0.0000228306,0.000007779538,0.00002930764,0.00001044173,0.00007986519,0.9979305,0.00001771462,0.00001746408,0.00155698],"study_design_scores_gemma":[0.000003923225,0.0001835597,0.002873907,0.000002308869,0.00001199519,0.0001279245,0.00001766181,0.0003461884,0.9957295,0.00001527155,0.0006831201,0.000004670778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879649,0.002908469,0.005373492,0.00007768858,0.0000185638,0.00008741237,0.001460117,0.0001087719,0.002000516],"genre_scores_gemma":[0.9789548,0.003057365,0.01135806,0.0001249344,0.00001903805,0.00009633711,0.003399146,0.00004324228,0.002947027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001804107,"threshold_uncertainty_score":0.003587246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0375174137056807,"score_gpt":0.3642945396092878,"score_spread":0.3267771259036071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}