{"id":"W2012980382","doi":"10.1021/tx400434b","title":"Epimers of Azaspiracids: Isolation, Structural Elucidation, Relative LC-MS Response, and <i>in Vitro</i> Toxicity of 37-<i>epi</i>-Azaspiracid-1","year":2014,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Marine Toxins and Detection Methods","field":"Environmental Science","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Epimer; Chemistry; Stereochemistry; Stereoisomerism; Nuclear magnetic resonance spectroscopy; EC50; In vitro; Chromatography; Biochemistry; Molecule; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004924349,0.0001426033,0.00038102,0.0002313244,0.00005924919,0.000008752017,0.0002760051,0.0002516674,0.0007061862],"category_scores_gemma":[0.004905909,0.0001352759,0.00004888243,0.0009891225,0.001212062,0.0002155422,0.0004231361,0.0006016431,0.00001060788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002420256,"about_ca_system_score_gemma":0.0000429534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002512484,"about_ca_topic_score_gemma":0.0001101141,"domain_scores_codex":[0.9963886,0.001566451,0.0006386451,0.0004794392,0.0004645685,0.0004622615],"domain_scores_gemma":[0.9967929,0.002504752,0.0001673279,0.0003205065,0.00006088642,0.0001535931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001597409,0.000074032,0.02680181,0.0000252004,0.0000045723,0.000001985031,0.0001899788,0.0001376609,0.9580852,0.000221863,0.00008216958,0.01277811],"study_design_scores_gemma":[0.0008274158,0.0003455725,0.09731022,0.00001432785,0.000002875243,0.000005585099,0.00005090281,0.00496099,0.8863549,0.008914676,0.001083668,0.0001288977],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920124,0.00003200581,0.000990157,0.0006705827,0.00004245149,0.0002960904,0.000006188137,0.00001017973,0.005939908],"genre_scores_gemma":[0.9906273,0.00001423493,0.009042023,0.0001048741,0.00002236002,0.00002940795,0.000003462482,0.00001186859,0.0001444334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07173035,"threshold_uncertainty_score":0.7732244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0375174137056807,"score_gpt":0.3642945396092878,"score_spread":0.3267771259036071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}