{"id":"W2012988934","doi":"10.1016/j.yjmcc.2008.05.008","title":"Wide long lasting perinuclear Ca2+ release events generated by an interaction between ryanodine and IP3 receptors in canine Purkinje cells","year":2008,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; Memorial University of Newfoundland","funders":"National Heart, Lung, and Blood Institute","keywords":"Ryanodine receptor; Purkinje cell; Nucleus; Biophysics; Molecular biology; Receptor; Internal medicine; Chemistry; Endocrinology; Cerebellum; Biology; Cell biology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002633972,0.0001381487,0.0002983698,0.0001397005,0.0002736857,0.0003043648,0.0002784013,0.0003997676,0.0005905463],"category_scores_gemma":[0.0003091148,0.0001596153,0.0002085346,0.0001202456,0.0003965219,0.0004362976,0.0005551071,0.0006201199,0.0001595068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002631126,"about_ca_system_score_gemma":0.0001079671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004354612,"about_ca_topic_score_gemma":0.0007663465,"domain_scores_codex":[0.9998773,0.00001575988,0.000007669303,0.00003214015,0.00003538075,0.00003166632],"domain_scores_gemma":[0.9996753,0.0001021527,0.00005339976,0.00004506954,0.00002625426,0.00009786899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003185319,0.00001175293,0.0003271219,0.00002571416,0.000008191118,0.0004563516,0.00004792598,0.0000632173,0.9978313,0.0001790046,0.00003247358,0.000698385],"study_design_scores_gemma":[0.0001872346,0.0007072944,0.1524229,0.00002433061,0.00007876512,0.003693009,0.0005506326,0.004324746,0.8337985,0.0008165556,0.003356887,0.00003925771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953834,0.0009554954,0.002805597,0.00005226446,0.00001900204,0.00001221767,0.00005466612,0.00003582416,0.0006814111],"genre_scores_gemma":[0.9985119,0.0001324566,0.0007935239,0.00003309932,0.00001845291,0.00001904087,0.00006357443,0.00001026504,0.0004176542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005905463,"threshold_uncertainty_score":0.001975536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01136885221591565,"score_gpt":0.2194112236455835,"score_spread":0.2080423714296679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}