{"id":"W2012988934","doi":"10.1016/j.yjmcc.2008.05.008","title":"Wide long lasting perinuclear Ca2+ release events generated by an interaction between ryanodine and IP3 receptors in canine Purkinje cells","year":2008,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; Memorial University of Newfoundland","funders":"National Heart, Lung, and Blood Institute","keywords":"Ryanodine receptor; Purkinje cell; Nucleus; Biophysics; Molecular biology; Receptor; Internal medicine; Chemistry; Endocrinology; Cerebellum; Biology; Cell biology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002739478,0.0001515268,0.0002897701,0.0001418671,0.00008807628,0.00001074038,0.0000649539,0.000196051,0.000009080543],"category_scores_gemma":[0.00007197572,0.0001452349,0.00008543698,0.0000965807,0.00006622376,0.0000177564,0.00004430371,0.0001948041,9.037839e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002761244,"about_ca_system_score_gemma":0.0000395718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002532833,"about_ca_topic_score_gemma":0.000007606014,"domain_scores_codex":[0.9988503,0.0002638078,0.0003568594,0.0002342231,0.0001158874,0.0001788548],"domain_scores_gemma":[0.9994207,0.00001508651,0.0001931202,0.0001079485,0.0001181714,0.0001449792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002100028,0.00002635321,0.04279788,0.00001280004,0.00009700539,0.0001612463,0.00008438155,0.002992253,0.9516937,0.00000194727,0.0005862726,0.001336191],"study_design_scores_gemma":[0.002777059,0.001746985,0.01340748,0.00004981599,0.0001081308,0.001521841,0.0003617702,0.0009423582,0.9566051,0.00001658079,0.02201508,0.0004478498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890735,0.001177366,0.009130807,0.00007606721,0.0003939717,0.00007928827,0.000004940787,0.000004162765,0.00005987447],"genre_scores_gemma":[0.9984261,0.0007003376,0.0001491799,0.00008486267,0.0003890358,0.000001503505,0.0001077038,0.0000227432,0.0001184797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02939041,"threshold_uncertainty_score":0.5922509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01136885221591565,"score_gpt":0.2194112236455835,"score_spread":0.2080423714296679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}