{"id":"W2012991731","doi":"10.1128/jvi.03114-13","title":"Inhibition of Dengue and Chikungunya Virus Infections by RIG-I-Mediated Type I Interferon-Independent Stimulation of the Innate Antiviral Response","year":2014,"lang":"en","type":"article","venue":"Journal of Virology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":133,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Institutes of Health; Canadian Institutes of Health Research; European Commission; National Institute for Health and Care Research","keywords":"Biology; Dengue virus; Chikungunya; Virology; RIG-I; Innate immune system; Dengue fever; Viral replication; Interferon; Virus; Antibody-dependent enhancement; Vesicular stomatitis virus; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002205054,0.000337508,0.0002079021,0.00007272398,0.00008819049,0.0002441911,0.0001736769,0.0002316705,0.001458271],"category_scores_gemma":[0.0001009291,0.00006564587,0.0002595534,0.00006567442,0.0001974215,0.0001440739,0.0001656299,0.000478035,0.000358006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001681505,"about_ca_system_score_gemma":0.0002134282,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001414066,"about_ca_topic_score_gemma":0.0002293857,"domain_scores_codex":[0.9998289,0.00004542559,0.0000219431,0.00002287207,0.00003977643,0.00004102921],"domain_scores_gemma":[0.9999424,0.00001911443,0.00001390394,0.0000085509,0.000006878892,0.000009035478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002564605,0.00005160576,0.0001924631,0.0001236464,0.000006833925,0.00002314634,0.000009547262,0.0001035579,0.996329,0.00006158544,0.00002947525,0.002812607],"study_design_scores_gemma":[0.0000334931,0.001207336,0.00314001,0.00001479849,0.00001650601,0.0001795946,0.00001533186,0.000434076,0.993386,0.00003366054,0.001535059,0.000004182545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869048,0.008325369,0.001999509,0.00007876653,0.00005506483,0.00005890087,0.0003513701,0.00003075319,0.002195598],"genre_scores_gemma":[0.994269,0.002328814,0.001772841,0.00005870367,0.00001636719,0.00005738756,0.0003658734,0.000005372327,0.001125584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001458271,"threshold_uncertainty_score":0.004878342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006232555037477557,"score_gpt":0.2368306173759354,"score_spread":0.2305980623384579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}