{"id":"W2013016540","doi":"10.1016/j.exphem.2010.07.006","title":"HoxA cluster is haploinsufficient for activity of hematopoietic stem and progenitor cells","year":2010,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"National Institutes of Health; Université de Genève; Leukemia and Lymphoma Society of Canada; Leukemia and Lymphoma Society","keywords":"Haploinsufficiency; Progenitor cell; Haematopoiesis; Stem cell; Cluster (spacecraft); Progenitor; Cell biology; Biology; Genetics; Computer science; Phenotype; Gene; Computer network","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002742172,0.0003208591,0.0003980922,0.001087588,0.000395786,0.0005087854,0.0004541494,0.0004517889,0.004371602],"category_scores_gemma":[0.0003173659,0.0004500748,0.0001693528,0.0003798959,0.0006534122,0.0002017365,0.0004252226,0.0007188322,0.0007794842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004507689,"about_ca_system_score_gemma":0.000372847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001460944,"about_ca_topic_score_gemma":0.00227781,"domain_scores_codex":[0.9995558,0.00006138838,0.00006018025,0.00008167709,0.0001531627,0.00008788518],"domain_scores_gemma":[0.9993879,0.0002070313,0.00007058728,0.00009557392,0.00004710735,0.0001919497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009293776,0.0000162145,0.0002354212,0.00001065583,0.000003573956,0.00006819538,0.000009396582,0.00004076445,0.9985642,0.0003281058,0.00004751937,0.0005829451],"study_design_scores_gemma":[0.00002104509,0.00004852028,0.003614084,0.000002619579,0.00001019293,0.0004105145,0.00002489508,0.000923756,0.9930665,0.00007985648,0.001793737,0.000004238826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925959,0.0006579303,0.003096522,0.0001374302,0.00003980142,0.00003059999,0.0007392658,0.0001856614,0.002517067],"genre_scores_gemma":[0.9905179,0.0001815992,0.002294649,0.00003758667,0.00001394213,0.00003127975,0.0008268449,0.0001334023,0.005962732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004371602,"threshold_uncertainty_score":0.01462448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00802453215269549,"score_gpt":0.2633972447512466,"score_spread":0.2553727125985511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}