{"id":"W2013016540","doi":"10.1016/j.exphem.2010.07.006","title":"HoxA cluster is haploinsufficient for activity of hematopoietic stem and progenitor cells","year":2010,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"National Institutes of Health; Université de Genève; Leukemia and Lymphoma Society of Canada; Leukemia and Lymphoma Society","keywords":"Haploinsufficiency; Progenitor cell; Haematopoiesis; Stem cell; Cluster (spacecraft); Progenitor; Cell biology; Biology; Genetics; Computer science; Phenotype; Gene; Computer network","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008722706,0.0001367673,0.0001911396,0.00003209542,0.00007089753,0.000005153383,0.00008700103,0.0002321117,0.00002132736],"category_scores_gemma":[0.000004602357,0.0001263399,0.000064735,0.00003020966,0.0002097672,0.000003955533,0.0001108471,0.00005504989,0.000005235601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005449513,"about_ca_system_score_gemma":0.00003159259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002156776,"about_ca_topic_score_gemma":0.000005454751,"domain_scores_codex":[0.9992495,0.00002589642,0.0001769827,0.0003116605,0.00005328577,0.0001827398],"domain_scores_gemma":[0.9996189,0.0000168697,0.00009428043,0.0001796243,0.00003367159,0.0000566433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001952372,0.0001957259,0.001448419,0.00004079251,0.00003303549,4.274608e-7,0.0002203229,2.841616e-7,0.9953976,0.001299009,0.0005997351,0.0005693643],"study_design_scores_gemma":[0.0006528736,0.0003291422,0.0004466607,0.000004808578,0.000006983315,0.0001013889,0.0001464034,0.00004525913,0.9948131,0.00003136736,0.003286368,0.0001356098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976385,0.0009565831,0.0003327022,0.0001269364,0.0003904066,0.0004234826,0.00001963384,0.000008459502,0.0001032868],"genre_scores_gemma":[0.9976541,0.000006351771,0.001773031,0.0001151392,0.00004490321,0.00008819238,0.0000246849,0.00001384945,0.0002797235],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002686633,"threshold_uncertainty_score":0.5151993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00802453215269549,"score_gpt":0.2633972447512466,"score_spread":0.2553727125985511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}