{"id":"W2013083005","doi":"10.1002/(sici)1098-2795(200004)55:4<387::aid-mrd5>3.0.co;2-p","title":"LiCl disrupts axial development in mouse but does not act through the ?-catenin/Lef-1 pathway","year":2000,"lang":"en","type":"article","venue":"Molecular Reproduction and Development","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Xenopus; Biology; Embryo; Lithium chloride; Cell biology; Zygote; Chimera (genetics); Beta-catenin; Salientia; Embryogenesis; Catenin; Wnt signaling pathway; Molecular biology; Signal transduction; Gene; Genetics; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000528031,0.0003464705,0.000229091,0.00006166175,0.0003188099,0.00008786143,0.0002583435,0.0001692543,0.0001629481],"category_scores_gemma":[0.00004925768,0.000242882,0.00005866836,0.0001601087,0.0001322959,0.0000189898,0.0001551661,0.0001863127,0.00006526629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007941553,"about_ca_system_score_gemma":0.0003581188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004289084,"about_ca_topic_score_gemma":0.00006046131,"domain_scores_codex":[0.9975464,0.0001000446,0.0005444231,0.00101038,0.0003667083,0.0004320465],"domain_scores_gemma":[0.9992304,0.000007285173,0.0001026702,0.0004825274,0.00008754399,0.00008961437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004475881,0.0002034183,0.002491756,0.00004462787,0.0001814477,0.00003256273,0.002922491,0.0002721667,0.8468449,0.00008015028,0.0006834881,0.1457955],"study_design_scores_gemma":[0.0004988235,0.00002776766,0.00270344,0.00001569119,0.000004491804,0.00002752252,0.0001303669,0.000002376213,0.7065497,0.00002795699,0.2896815,0.0003303294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958274,0.0008531562,0.0006849192,0.0008876986,0.0003005622,0.0004308857,0.000003523755,0.00004522004,0.0009665738],"genre_scores_gemma":[0.9752316,0.000311811,0.005590371,0.0008410421,0.0001939689,0.0002189601,0.0001258941,0.00004763551,0.01743874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.288998,"threshold_uncertainty_score":0.9904441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01271011815134671,"score_gpt":0.2361035751931555,"score_spread":0.2233934570418088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}