{"id":"W2013083005","doi":"10.1002/(sici)1098-2795(200004)55:4<387::aid-mrd5>3.0.co;2-p","title":"LiCl disrupts axial development in mouse but does not act through the ?-catenin/Lef-1 pathway","year":2000,"lang":"en","type":"article","venue":"Molecular Reproduction and Development","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Xenopus; Biology; Embryo; Lithium chloride; Cell biology; Zygote; Chimera (genetics); Beta-catenin; Salientia; Embryogenesis; Catenin; Wnt signaling pathway; Molecular biology; Signal transduction; Gene; Genetics; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002611458,0.0004245231,0.000242171,0.0007915843,0.0002870929,0.0004904454,0.0004022528,0.000541679,0.002773047],"category_scores_gemma":[0.0001588816,0.0003133609,0.0002976198,0.0002687566,0.0005771635,0.0002350704,0.0002668359,0.0008643554,0.0008188834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006707768,"about_ca_system_score_gemma":0.0005322881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001254243,"about_ca_topic_score_gemma":0.002639763,"domain_scores_codex":[0.9996356,0.00006407026,0.00004125305,0.00005595566,0.0001176603,0.00008547709],"domain_scores_gemma":[0.9996403,0.00004904245,0.0001377885,0.00003337198,0.00001710778,0.0001222992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009287961,0.00003346046,0.0002005899,0.00003027375,0.000005510479,0.00008260404,0.00001792981,0.0000415025,0.9984174,0.0002437833,0.00005445473,0.0007796981],"study_design_scores_gemma":[0.00002747895,0.0002617227,0.002869241,0.00001156441,0.00001790444,0.0003497802,0.00002660284,0.0004319038,0.9930549,0.00005190564,0.002893088,0.000003938417],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899085,0.001697828,0.002151682,0.00031994,0.00003727751,0.00004505386,0.0008921631,0.0003451032,0.004602522],"genre_scores_gemma":[0.9835871,0.001060816,0.002112447,0.0001543798,0.00001258115,0.00008068712,0.001020013,0.0001145345,0.0118575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002773047,"threshold_uncertainty_score":0.009276748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01271011815134671,"score_gpt":0.2361035751931555,"score_spread":0.2233934570418088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}