{"id":"W2013095752","doi":"10.1002/cbic.201300134","title":"Quality Control Certification of RNA Aptamer‐Based Detection","year":2013,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Aptamer; RNA; DNA; Nuclease; Molecular beacon; Chemistry; Molecular recognition; Biosensor; Riboswitch; Molecular biology; Biophysics; Oligonucleotide; Computational biology; Biochemistry; Biology; Non-coding RNA; Gene; Molecule","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001533188,0.0001197131,0.0001595641,0.00003666901,0.00003971609,0.00001124764,0.000105161,0.0001547073,0.00000708699],"category_scores_gemma":[0.0001368562,0.0001081973,0.0001276431,0.0001105736,0.0001053561,0.000003769832,0.00001854111,0.00005528171,0.000006693921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001471355,"about_ca_system_score_gemma":0.00002136338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004582897,"about_ca_topic_score_gemma":0.000006877151,"domain_scores_codex":[0.9991724,0.00004184217,0.0002675403,0.0002694536,0.0001102918,0.000138395],"domain_scores_gemma":[0.9991124,0.00001408922,0.0001916893,0.0003960344,0.0002366882,0.0000490986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003298351,0.00005430702,0.0002436082,0.00001602494,0.00002678016,5.331721e-8,0.000002975755,0.000002614304,0.9833028,0.00000679964,0.0002147193,0.01609639],"study_design_scores_gemma":[0.0003048214,0.00007737095,0.002185315,0.000007042755,0.00001758297,7.964269e-7,0.00002528534,0.0003015023,0.9962142,0.00007681799,0.0006521757,0.0001371459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9665433,0.00009571613,0.03219834,0.0001783067,0.00003335354,0.0001793004,0.000008780018,0.000041506,0.0007214265],"genre_scores_gemma":[0.9973104,0.00001427874,0.002130955,0.0001810653,0.00007450324,0.00002713571,0.0000727551,0.00001246434,0.0001764256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03076714,"threshold_uncertainty_score":0.4412159,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01446979759234215,"score_gpt":0.2788987412527004,"score_spread":0.2644289436603583,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}