{"id":"W2013098933","doi":"10.1038/ncb1983","title":"UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit","year":2009,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":247,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Cancer Research UK; Wellcome Trust","keywords":"Mitosis; Cell biology; Mitotic exit; Spindle checkpoint; Ubiquitin ligase; Ubiquitin; Biology; Anaphase; Anaphase-promoting complex; Proteasome; Spindle apparatus; Biochemistry; Cell cycle; Cell division; Cell","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001383924,0.0002947382,0.0002413398,0.0001404718,0.00008714681,0.00002247637,0.0003587703,0.0008335811,0.00002844231],"category_scores_gemma":[0.00007505347,0.0002536094,0.0001210485,0.0002013124,0.00005382402,0.000002251895,0.00006312307,0.0004466965,0.00008238211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001676622,"about_ca_system_score_gemma":0.00004394658,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006369814,"about_ca_topic_score_gemma":0.00003926561,"domain_scores_codex":[0.9984899,0.00006845276,0.0002255148,0.0006435804,0.00007018768,0.0005023513],"domain_scores_gemma":[0.9992171,0.00001696377,0.00007648195,0.0004486972,0.00009002262,0.0001507446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001032688,0.0001407485,0.0002368719,0.00001058457,0.00001980046,0.000008056458,0.00002736385,0.00002489937,0.9916346,0.0009039036,0.003725621,0.00316428],"study_design_scores_gemma":[0.0003608636,0.001506639,0.0009320281,0.00001479125,0.00001322,0.00001208752,0.00002064835,0.00002285987,0.8898421,0.000227078,0.1067418,0.0003059232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905981,0.001662209,0.000137286,0.001318689,0.0003686539,0.0003873057,0.000049199,0.00003828522,0.005440257],"genre_scores_gemma":[0.990903,0.0003958219,0.0009238942,0.005481873,0.0005070407,0.00001619654,0.0004796057,0.0000249025,0.00126766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1030162,"threshold_uncertainty_score":0.9999916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004834147945571323,"score_gpt":0.245212997230717,"score_spread":0.2403788492851457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}