{"id":"W2013107151","doi":"10.1016/j.bbmt.2013.11.001","title":"Allogeneic Human Mesenchymal Stem Cell Therapy (Remestemcel-L, Prochymal) as a Rescue Agent for Severe Refractory Acute Graft-versus-Host Disease in Pediatric Patients","year":2013,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":246,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; Centre Hospitalier Universitaire Sainte-Justine","funders":"Osiris Therapeutics","keywords":"Medicine; Refractory (planetary science); Hematopoietic stem cell transplantation; Internal medicine; Mesenchymal stem cell; Graft-versus-host disease; Stem cell; Transplantation; Population; Disease; Cord blood; Surgery; Gastroenterology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003160624,0.0002284661,0.0004332196,0.0001296703,0.0001192096,0.0001767295,0.0001651908,0.000169102,0.0004586538],"category_scores_gemma":[0.0002887537,0.00005831656,0.000210458,0.0001541053,0.000167314,0.0001292067,0.0001565807,0.0003210681,0.0001716525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001869707,"about_ca_system_score_gemma":0.0002951814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001917718,"about_ca_topic_score_gemma":0.0005753266,"domain_scores_codex":[0.9998386,0.00006978406,0.00001759076,0.00002074387,0.000025684,0.00002761686],"domain_scores_gemma":[0.9998248,0.00003615862,0.00006578393,0.00001039012,0.000007594569,0.00005525844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.02420522,0.003055774,0.3432687,0.0009353406,0.000355117,0.006245788,0.000610308,0.001972279,0.2400918,0.0007210516,0.003063951,0.3754748],"study_design_scores_gemma":[0.005083546,0.1717747,0.6747791,0.000193043,0.0004845374,0.03671435,0.0005963232,0.004228443,0.08592951,0.0002300088,0.01994916,0.00003729686],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996106,0.003194031,0.0002083987,0.00004161461,0.000006042294,0.00003899962,0.00007679741,0.00001118324,0.0003168722],"genre_scores_gemma":[0.9965253,0.001744526,0.001159766,0.0001106534,0.00002943431,0.00005212758,0.0002379526,0.000004003289,0.0001361958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004586538,"threshold_uncertainty_score":0.001671553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02384220199907952,"score_gpt":0.2883727978792496,"score_spread":0.26453059588017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}