{"id":"W2013131528","doi":"10.1021/tx200291p","title":"Comparative Toxicity of Arsenic Metabolites in Human Bladder Cancer EJ-1 Cells","year":2011,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Arsenic contamination and mitigation","field":"Environmental Science","cited_by":156,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Arsenite; Arsenic; Chemistry; Arsenate; Glutathione; Arsenic toxicity; Carcinogen; Toxicity; DNA damage; Reactive oxygen species; Urine; Intracellular; Carcinogenesis; Biochemistry; Genotoxicity; Cytotoxicity; In vitro; DNA; Enzyme; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000703614,0.00007786333,0.0002193255,0.000119401,0.00002860049,0.000003093549,0.0002469128,0.0001237631,0.006497165],"category_scores_gemma":[0.00009282392,0.0000744689,0.00003019374,0.0004538903,0.0007628009,0.00008855729,0.0002339629,0.0003603888,0.00006957547],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002830246,"about_ca_system_score_gemma":0.00003757097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007337901,"about_ca_topic_score_gemma":0.002392493,"domain_scores_codex":[0.9985687,0.0002466788,0.0002820661,0.0002701528,0.0002671379,0.0003653282],"domain_scores_gemma":[0.9994617,0.0002247029,0.00005108548,0.000148242,0.00002474032,0.00008950927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002633211,0.0002934335,0.01043522,0.000005390921,0.000004501849,0.000004862048,0.001690177,0.000006699427,0.9845651,0.00121552,0.0003650427,0.001387705],"study_design_scores_gemma":[0.0003772754,0.00005353592,0.0555176,0.000009192941,0.000001802499,4.748988e-7,0.000270739,0.0002587843,0.9400218,0.002892136,0.0005281621,0.00006854017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9716119,0.00004687097,0.000008478541,0.0001480338,0.00002919341,0.0002450863,0.000004067219,0.000006000494,0.02790033],"genre_scores_gemma":[0.9991385,0.00002890927,0.0002653925,0.00006055694,0.00001167372,0.00008456851,0.000002963341,0.000004752937,0.0004026563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04508238,"threshold_uncertainty_score":0.9944111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1747808559276993,"score_gpt":0.4135799399211236,"score_spread":0.2387990839934243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}