{"id":"W2013131528","doi":"10.1021/tx200291p","title":"Comparative Toxicity of Arsenic Metabolites in Human Bladder Cancer EJ-1 Cells","year":2011,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Arsenic contamination and mitigation","field":"Environmental Science","cited_by":156,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Arsenite; Arsenic; Chemistry; Arsenate; Glutathione; Arsenic toxicity; Carcinogen; Toxicity; DNA damage; Reactive oxygen species; Urine; Intracellular; Carcinogenesis; Biochemistry; Genotoxicity; Cytotoxicity; In vitro; DNA; Enzyme; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002938638,0.0002972211,0.0004737556,0.0004444117,0.0003495304,0.0002568362,0.0002218589,0.0004350755,0.00120267],"category_scores_gemma":[0.0001486744,0.0001898291,0.0004572627,0.0008065842,0.0001396495,0.0002236773,0.0001958849,0.0004298722,0.0003338429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000265316,"about_ca_system_score_gemma":0.0002943907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002495656,"about_ca_topic_score_gemma":0.00271586,"domain_scores_codex":[0.9996036,0.00008423326,0.00006189512,0.00007685737,0.0001162754,0.00005718187],"domain_scores_gemma":[0.9998728,0.00002710712,0.00001835626,0.00001604883,0.00004773317,0.00001796519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002730271,0.0001172027,0.001129899,0.0001668935,0.00002610634,0.00009600737,0.0001478757,0.0001977093,0.9956501,0.0001113245,0.0001545887,0.001929323],"study_design_scores_gemma":[0.00003659756,0.002598188,0.01733295,0.00001606802,0.0001033762,0.0004859834,0.0002687036,0.001594272,0.9718688,0.00008020933,0.005592518,0.00002230253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890287,0.005343497,0.001945736,0.0001315556,0.00006310627,0.00006441331,0.00160314,0.00007196042,0.001748063],"genre_scores_gemma":[0.9775594,0.004934576,0.00474535,0.0001728714,0.00002475736,0.000230535,0.005112637,0.00002092403,0.007199046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002495656,"threshold_uncertainty_score":0.004962265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1747808559276993,"score_gpt":0.4135799399211236,"score_spread":0.2387990839934243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}