{"id":"W2013168905","doi":"10.1038/modpathol.2014.143","title":"Clinicopathological analysis of endometrial carcinomas harboring somatic POLE exonuclease domain mutations","year":2014,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":218,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of Calgary","funders":"","keywords":"PTEN; Endometrial cancer; Nuclear atypia; Pathology; Hematopathology; Adenocarcinoma; Biology; Somatic cell; Serous fluid; Carcinoma; Cancer; Medicine; Cancer research; Internal medicine; Immunohistochemistry; Chromosome; Gene; Genetics; Cytogenetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005558899,0.000257537,0.0002134864,0.001353761,0.0005058504,0.000488635,0.0002002478,0.0004385108,0.001881798],"category_scores_gemma":[0.001315859,0.0002079469,0.0002962112,0.0008899506,0.0004492996,0.0003613289,0.0002975054,0.0002086751,0.0003182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002367424,"about_ca_system_score_gemma":0.0002343927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000600989,"about_ca_topic_score_gemma":0.001049613,"domain_scores_codex":[0.9997757,0.00004223609,0.00003900732,0.00004921797,0.00003329038,0.00006061274],"domain_scores_gemma":[0.9994042,0.0001650614,0.0001570727,0.00005325205,0.00007257414,0.0001478909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009188537,0.00003359308,0.9663176,0.00004321638,0.00005551471,0.01723986,0.0001832199,0.0001360647,0.008989842,0.0001426041,0.0003065411,0.005633099],"study_design_scores_gemma":[0.00002266092,0.0002062021,0.9379318,0.00001382492,0.0001149569,0.05673131,0.0005997054,0.0005326195,0.001752643,0.0001937438,0.00188511,0.00001535047],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970983,0.0007864947,0.0002518635,0.00003819088,0.00001201029,0.00001002787,0.0001823955,0.000009240378,0.001611569],"genre_scores_gemma":[0.9992921,0.0001721804,0.0001234933,0.00001501647,0.00001424755,0.000004984224,0.0001347973,0.000001913497,0.0002411933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001881798,"threshold_uncertainty_score":0.006295264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04191974750568531,"score_gpt":0.3179876011557045,"score_spread":0.2760678536500192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}