{"id":"W2013168905","doi":"10.1038/modpathol.2014.143","title":"Clinicopathological analysis of endometrial carcinomas harboring somatic POLE exonuclease domain mutations","year":2014,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":218,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of Calgary","funders":"","keywords":"PTEN; Endometrial cancer; Nuclear atypia; Pathology; Hematopathology; Adenocarcinoma; Biology; Somatic cell; Serous fluid; Carcinoma; Cancer; Medicine; Cancer research; Internal medicine; Immunohistochemistry; Chromosome; Gene; Genetics; Cytogenetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005573446,0.000181286,0.001026565,0.0008645434,0.00007108657,0.000008407316,0.0001195724,0.000171678,0.0003319588],"category_scores_gemma":[0.001025726,0.0001427721,0.0004538172,0.001335643,0.0001731783,0.00004035546,0.00007079561,0.0001732226,0.00003732049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000690786,"about_ca_system_score_gemma":0.00004573387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004090251,"about_ca_topic_score_gemma":0.0000167533,"domain_scores_codex":[0.9980399,0.0003127063,0.0006233507,0.0004290325,0.0002755403,0.0003194527],"domain_scores_gemma":[0.9984262,0.0006027324,0.0002121831,0.0004703823,0.0000943421,0.000194144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002039994,0.002126145,0.8899873,0.0001567116,0.001463728,0.0008989422,0.001462158,0.0006346309,0.03355281,0.003199593,0.00001631202,0.06446165],"study_design_scores_gemma":[0.01383693,0.002439848,0.9560903,0.00003193053,0.006426406,0.00008604527,0.0001240263,0.008525148,0.001992033,0.009903966,0.0002522547,0.0002910729],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800435,0.0002743989,0.01577333,0.0002417873,0.0002067717,0.00027483,0.00004697987,0.00006350289,0.003074858],"genre_scores_gemma":[0.9946346,0.00001647687,0.004633126,0.0002963578,0.0001718057,0.00004874285,0.00008859127,0.00001872701,0.00009156125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06610301,"threshold_uncertainty_score":0.5822077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04191974750568531,"score_gpt":0.3179876011557045,"score_spread":0.2760678536500192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}