{"id":"W2013175858","doi":"10.3389/fgene.2012.00096","title":"The secret language of destiny: stress imprinting and transgenerational origins of disease","year":2012,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Canadian Institutes of Health Research; Alberta Innovates","keywords":"Epigenetics; Disease; DNA methylation; Biology; Transgenerational epigenetics; Genetics; Bioinformatics; Computational biology; Gene; Medicine; Gene expression; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004500017,0.0002603564,0.0002824261,0.0003564621,0.0002904681,0.0007550238,0.0003388202,0.0005176666,0.001339219],"category_scores_gemma":[0.0005725455,0.0001152875,0.0001735317,0.0001990778,0.001127976,0.001012084,0.0007407343,0.0007124121,0.0002065351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000328356,"about_ca_system_score_gemma":0.000265522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004698067,"about_ca_topic_score_gemma":0.000699017,"domain_scores_codex":[0.9998909,0.00002138817,0.000007429979,0.00003515125,0.00002450137,0.00002055319],"domain_scores_gemma":[0.9996964,0.00007825944,0.00009893137,0.00004631915,0.00002068814,0.00005948409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0004624819,0.00003376365,0.01426202,0.000237504,0.00004387827,0.001373415,0.0005908584,0.0004341967,0.8580706,0.05883433,0.0008138883,0.0648431],"study_design_scores_gemma":[0.00006122348,0.0006857054,0.1713323,0.0002518404,0.0002198301,0.009213519,0.001355907,0.00825965,0.5983811,0.1423173,0.06777484,0.0001468136],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8711529,0.03991867,0.06212849,0.009485856,0.0006670286,0.00003768659,0.000581512,0.0003831921,0.01564455],"genre_scores_gemma":[0.9836026,0.007490522,0.004332771,0.0004272195,0.0001196334,0.00001287214,0.0001368264,0.00003841666,0.003839188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001339219,"threshold_uncertainty_score":0.004480183,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007014568345871156,"score_gpt":0.2473704955021047,"score_spread":0.2403559271562335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}