{"id":"W2013175858","doi":"10.3389/fgene.2012.00096","title":"The secret language of destiny: stress imprinting and transgenerational origins of disease","year":2012,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Canadian Institutes of Health Research; Alberta Innovates","keywords":"Epigenetics; Disease; DNA methylation; Biology; Transgenerational epigenetics; Genetics; Bioinformatics; Computational biology; Gene; Medicine; Gene expression; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002056219,0.00006924051,0.00008055339,0.00002638695,0.00003525583,0.000005931436,0.00008056394,0.00005130444,0.000001185314],"category_scores_gemma":[0.00005342007,0.00005834866,0.00002955794,0.00004995364,0.00009431186,0.000002134834,0.00003370957,0.00003721945,5.67913e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008048847,"about_ca_system_score_gemma":0.00003880226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001227166,"about_ca_topic_score_gemma":0.00002136375,"domain_scores_codex":[0.9994351,0.00004724916,0.0001877573,0.00009722254,0.00009371837,0.000138956],"domain_scores_gemma":[0.9996486,0.00001456323,0.00007584256,0.0001599365,0.00003979573,0.00006123869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003664135,0.00003657175,0.6880876,0.00003431328,0.0000198117,1.39001e-7,0.0002863384,0.0007223669,0.3003743,0.0002119182,0.00003558237,0.0101545],"study_design_scores_gemma":[0.0003200576,0.0000662496,0.1827309,0.00001366711,0.00002494465,2.324122e-7,0.0003452001,0.001410263,0.8119903,0.0001794807,0.002807803,0.0001108364],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9620224,0.02298683,0.01458708,0.00001942341,0.0001946162,0.00009312982,0.00003791417,0.000001296077,0.00005734513],"genre_scores_gemma":[0.987007,0.001803926,0.01098453,0.000006396659,0.0001108377,0.000004950164,0.00004259633,0.000009375475,0.00003038187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5116161,"threshold_uncertainty_score":0.2379389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007014568345871156,"score_gpt":0.2473704955021047,"score_spread":0.2403559271562335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}