{"id":"W2013205499","doi":"10.1074/jbc.m402666200","title":"The Role of Interleukin 1 Receptor-associated Kinase-4 (IRAK-4) Kinase Activity in IRAK-4-mediated Signaling","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Kinase; Signal transduction; Interleukin-1 receptor; Chemistry; Cell biology; Biology; Interleukin; Immunology; Cytokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001011888,0.0001559751,0.0003766647,0.00004817141,0.00009836384,0.00001288687,0.0003272484,0.0004679745,0.000157151],"category_scores_gemma":[0.001536434,0.00009610236,0.0001905917,0.000192549,0.0002415047,0.00008134356,0.00006770265,0.0007000925,0.0000208697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000191277,"about_ca_system_score_gemma":0.0001322373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000248195,"about_ca_topic_score_gemma":0.000003139473,"domain_scores_codex":[0.9985731,0.0002684876,0.0006806463,0.0001305798,0.00006245168,0.0002846819],"domain_scores_gemma":[0.9983981,0.0005239855,0.0007504079,0.0001379718,0.0001629493,0.00002658625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001152351,0.0002492801,0.002049759,0.000008010222,0.00009426065,0.00001153718,0.0001209921,0.00002857763,0.9930825,0.00001646812,0.00003364034,0.003152671],"study_design_scores_gemma":[0.00146958,0.0002958264,0.004383619,0.000139977,0.00001257332,0.0000340326,0.0004336158,0.000002235406,0.9898667,0.0004186733,0.002833705,0.0001094663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962981,0.002933455,0.00001258937,0.0002593953,0.0001456923,0.0000674475,0.000008597582,0.00001288752,0.0002618255],"genre_scores_gemma":[0.9994436,0.0003704332,0.00001886601,0.00002159795,0.00003965049,0.000003167862,0.0000285182,0.000006587958,0.00006759502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003215757,"threshold_uncertainty_score":0.3918941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01134495705186749,"score_gpt":0.2271910478248918,"score_spread":0.2158460907730243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}