{"id":"W2013221473","doi":"10.1016/j.cellsig.2009.07.007","title":"F-BAR-containing adaptor CIP4 localizes to early endosomes and regulates Epidermal Growth Factor Receptor trafficking and downregulation","year":2009,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"National Institutes of Health","keywords":"Endosome; Cell biology; Endocytosis; Internalization; Epidermal growth factor receptor; Downregulation and upregulation; Gene silencing; Biology; A431 cells; Epidermal growth factor; Clathrin; Signal transducing adaptor protein; MAPK/ERK pathway; Chemistry; Kinase; Signal transduction; Cell; Receptor; Cell cycle; Intracellular; Biochemistry; Oncogene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001647777,0.0004735235,0.0004058652,0.0008513206,0.0007373249,0.001007457,0.0006885523,0.00066096,0.003376597],"category_scores_gemma":[0.0003027825,0.0004640491,0.00058595,0.0003219733,0.0004843959,0.0006686838,0.0008474592,0.001361913,0.001779389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001688566,"about_ca_system_score_gemma":0.0005376086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001774269,"about_ca_topic_score_gemma":0.001793605,"domain_scores_codex":[0.9996738,0.00001957153,0.00001356993,0.00005032517,0.00008696836,0.0001556356],"domain_scores_gemma":[0.9997804,0.00002146523,0.00005048975,0.00002907695,0.00005112283,0.0000674047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002877575,0.00002125076,0.0003262302,0.00003798625,0.000009044968,0.0001626276,0.000008149882,0.00009973039,0.9969389,0.0004235194,0.0002624108,0.001422405],"study_design_scores_gemma":[0.00003416521,0.00005436206,0.0168534,0.000007505001,0.00002230946,0.0006863123,0.00006322705,0.002040101,0.9747014,0.0002120281,0.005308094,0.00001713922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842409,0.002400718,0.005009996,0.0004299122,0.00009229039,0.00003403067,0.0006749814,0.0003655977,0.006751431],"genre_scores_gemma":[0.9839178,0.0008251125,0.002364994,0.000154104,0.00003128364,0.00004711425,0.001301259,0.000173912,0.01118443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003376597,"threshold_uncertainty_score":0.0122515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01103704847467293,"score_gpt":0.2092077989858915,"score_spread":0.1981707505112186,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}