{"id":"W2013301331","doi":"10.1016/s0006-291x(02)00599-5","title":"Lack of nitric oxide synthase depresses ion transporting enzyme function in cardiac muscle","year":2002,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of Neurological Disorders and Stroke; American Heart Association","keywords":"ATPase; Cardiac muscle; Nitric oxide synthase; Chemistry; Nitric oxide; Western blot; Enzyme; Gene isoform; Endoplasmic reticulum; Plasma membrane Ca2+ ATPase; Nitric Oxide Synthase Type III; Ion transporter; Biochemistry; Enos; Biology; Endocrinology; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003376394,0.000091583,0.0001425503,0.0001068863,0.0001222142,0.0000152202,0.0002253372,0.0001376021,0.00001931382],"category_scores_gemma":[0.0003920112,0.0000848244,0.00007888093,0.0004314681,0.0003460914,0.000009846577,0.0001374389,0.0002192698,0.000007924154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001613057,"about_ca_system_score_gemma":0.00001710713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006569265,"about_ca_topic_score_gemma":0.000006220489,"domain_scores_codex":[0.9988849,0.0001842614,0.0002513149,0.0002436193,0.0002252547,0.0002106189],"domain_scores_gemma":[0.998987,0.0001575367,0.00005090854,0.0005256258,0.0001827046,0.00009618556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005057802,0.0002966091,0.001045977,0.00002889222,0.00001007947,1.782171e-7,0.00002487893,0.000005726783,0.9935979,0.0003552837,0.0008189689,0.003764954],"study_design_scores_gemma":[0.0005614602,0.0001992158,0.04715974,0.00006513084,0.00002012291,0.000001081586,0.0002237397,0.003716013,0.931816,0.0004002895,0.01562424,0.0002129421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965091,0.001878923,0.0001778712,0.0006327257,0.00002428098,0.0001717822,0.00002043543,0.00001058231,0.0005743414],"genre_scores_gemma":[0.9975721,0.001768014,0.0001686771,0.00002750801,0.0001179485,0.00004520174,0.000137162,0.000009944061,0.0001534276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06178185,"threshold_uncertainty_score":0.3459039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.108636491224394,"score_gpt":0.3481368872079998,"score_spread":0.2395003959836058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}