{"id":"W2013308243","doi":"10.1002/iub.187","title":"GSK‐3: A key player in neurodegeneration and memory","year":2009,"lang":"en","type":"review","venue":"IUBMB Life","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Alzheimer's Research Trust; Alzheimer Society; Wellcome Trust","keywords":"Neurodegeneration; GSK-3; Neuroscience; Hyperphosphorylation; Long-term potentiation; Cyclin-dependent kinase 5; Biology; Cell biology; Kinase; Chemistry; Protein kinase A; Medicine; Disease; Biochemistry; Internal medicine; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002549544,0.001195273,0.001149857,0.001354884,0.0002932439,0.0009655227,0.0007483491,0.001101905,0.003488949],"category_scores_gemma":[0.0002378867,0.0002146774,0.0003243604,0.002177421,0.0006862277,0.001147114,0.0006485417,0.001034423,0.004596034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006811899,"about_ca_system_score_gemma":0.000981602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006414839,"about_ca_topic_score_gemma":0.0008698666,"domain_scores_codex":[0.9998807,0.00001625208,0.00001641386,0.00002246501,0.00004916975,0.00001496569],"domain_scores_gemma":[0.9999281,0.00001537228,0.0000178477,0.000004260047,0.00001853426,0.00001587608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001373311,0.00004074211,0.0002198135,0.007401075,0.00005932166,0.0003342231,0.00006324425,0.0003129563,0.005221619,0.003977446,0.02761379,0.9546185],"study_design_scores_gemma":[0.00003423347,0.00007825889,0.001134818,0.001183514,0.00005115587,0.001413114,0.00006242641,0.00005283448,0.001390973,0.005595194,0.9889871,0.00001617641],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002459591,0.9972891,0.0001564769,0.0002505449,0.0001794565,0.000005099872,0.00002318623,0.00001896521,0.001831214],"genre_scores_gemma":[0.002024635,0.9960327,0.0001779178,0.0001312823,0.0001542403,0.000007778099,0.00004938007,0.000002058106,0.001419981],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003488949,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08323079412608174,"score_gpt":0.3829624640397941,"score_spread":0.2997316699137123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}