{"id":"W2013331123","doi":"10.1083/jcb.200709030","title":"Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis","year":2008,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":130,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Human Genome Research Institute","keywords":"Biology; RNA-binding protein; Cytoplasm; Stress granule; Cell biology; Apoptosis; Cleavage (geology); Caspase 2; Activator (genetics); Molecular biology; Caspase; Programmed cell death; RNA; Messenger RNA; Translation (biology); Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001917287,0.0002974839,0.0002277068,0.0001357373,0.00021201,0.0003411454,0.0001512371,0.0002133226,0.0008592452],"category_scores_gemma":[0.0002470279,0.0001586079,0.0002743665,0.00009152349,0.0003577295,0.0002731849,0.0002501002,0.0005058805,0.0005535379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003378879,"about_ca_system_score_gemma":0.000211887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000172722,"about_ca_topic_score_gemma":0.0002509335,"domain_scores_codex":[0.9998349,0.00003526465,0.00001422555,0.00004075495,0.00004416965,0.00003062479],"domain_scores_gemma":[0.9998233,0.00002959386,0.00005818511,0.00002234778,0.00003173332,0.00003499048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000699137,0.000007617219,0.0002701921,0.00001444488,0.000001592696,0.00009796998,0.00001065984,0.00004735798,0.9985,0.0001610008,0.00001639643,0.0008029977],"study_design_scores_gemma":[0.00001771046,0.0001243092,0.005144028,0.000003631319,0.000008137847,0.0005989078,0.00002894617,0.001229397,0.991651,0.0002595719,0.00093102,0.00000329352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879525,0.002103344,0.007830014,0.0001865748,0.00002922563,0.00001376591,0.00007498819,0.0000637367,0.001745777],"genre_scores_gemma":[0.9948731,0.0009209441,0.002849505,0.00004009305,0.00001378212,0.00001142715,0.0001247491,0.0000158267,0.001150651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008592452,"threshold_uncertainty_score":0.002874434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01361998317910177,"score_gpt":0.2588571514614979,"score_spread":0.2452371682823961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}