{"id":"W2013359081","doi":"10.1210/en.2011-1488","title":"Twist Modulates Human Trophoblastic Cell Invasion via Regulation of N-Cadherin","year":2011,"lang":"en","type":"article","venue":"Endocrinology","topic":"Kruppel-like factors research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Cadherin; Biology; Placentation; Matrigel; Twist transcription factor; Small interfering RNA; Trophoblast; Gene knockdown; Cell biology; Cell growth; Cell; Cell migration; Cancer research; Cell culture; Transforming growth factor; Gentamicin protection assay; Internal medicine; Metastasis; Transfection; Downregulation and upregulation; Placenta; Gene; Epithelial–mesenchymal transition; Cancer; Genetics; Fetus; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001114192,0.0001897887,0.0001614505,0.0002071866,0.0001386053,0.0002564921,0.00006832278,0.000108813,0.001464553],"category_scores_gemma":[0.0001233407,0.00010171,0.0001860428,0.0001295778,0.0001657784,0.0001232808,0.0001180041,0.0003032604,0.0002683846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001709456,"about_ca_system_score_gemma":0.0001308963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005638024,"about_ca_topic_score_gemma":0.0009679215,"domain_scores_codex":[0.999899,0.00002915972,0.000007354417,0.00001223856,0.00002017349,0.0000319746],"domain_scores_gemma":[0.9999497,0.00001325344,0.00001399826,0.000004068225,0.000006092045,0.00001291966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002508422,0.00003187081,0.0005091895,0.00004852596,0.000004285892,0.0000746713,0.00003373247,0.00005404064,0.9979907,0.00007245746,0.00007422599,0.0008555964],"study_design_scores_gemma":[0.00005310626,0.000708067,0.03393441,0.00001757191,0.00003920754,0.0004300344,0.0001836449,0.00145924,0.9576439,0.00009212881,0.005427706,0.00001114051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994108,0.002283845,0.0008112089,0.00009702499,0.00003165437,0.00002148978,0.0003359567,0.00003124903,0.002279549],"genre_scores_gemma":[0.9952509,0.00187558,0.0005619197,0.00007039612,0.00001082132,0.00002843197,0.0004786493,0.000008390163,0.001714892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001464553,"threshold_uncertainty_score":0.004899383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0289670770780915,"score_gpt":0.2618578780179309,"score_spread":0.2328908009398394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}