{"id":"W2013418801","doi":"10.1089/104303403322167984","title":"Size-Exclusion Chromatography Purification of High-Titer Vesicular Stomatitis Virus G Glycoprotein-Pseudotyped Retrovectors for Cell and Gene Therapy Applications","year":2003,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Biotechnology Research Institute","funders":"","keywords":"Vesicular stomatitis virus; Biology; Transduction (biophysics); Genetic enhancement; Retrovirus; Virus; Ultracentrifuge; Cell culture; Molecular biology; Virology; Viral vector; Vesicular Stomatitis; Biochemistry; Gene; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004666961,0.0004887613,0.0003549927,0.0003439024,0.0002037323,0.0007085617,0.0004773258,0.0003532943,0.0004305347],"category_scores_gemma":[0.0003935675,0.0001953589,0.0004073917,0.0002557512,0.0003159016,0.0003516015,0.0003004215,0.0009894313,0.0006397238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004504384,"about_ca_system_score_gemma":0.0004649595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004708323,"about_ca_topic_score_gemma":0.0008414865,"domain_scores_codex":[0.9996611,0.00006444245,0.00004039234,0.00004113283,0.000169198,0.00002376378],"domain_scores_gemma":[0.9997856,0.00004737601,0.00003961511,0.00002667761,0.00006051919,0.00004020727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001396519,0.00001905356,0.0001806552,0.00003076659,0.000006891954,0.00003265269,0.00001735476,0.0001612302,0.9963568,0.0002391585,0.00008426778,0.002857073],"study_design_scores_gemma":[0.000008787868,0.00009727882,0.0007424398,0.000004928081,0.00002037737,0.000241977,0.000009561345,0.001588791,0.9913772,0.00009242183,0.005809078,0.00000724835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6279538,0.003798056,0.3626525,0.000467085,0.0001937786,0.0005720264,0.0009428494,0.001265854,0.002154132],"genre_scores_gemma":[0.6745245,0.004802605,0.3066713,0.0003434798,0.00007685369,0.0004125431,0.005127564,0.0002980558,0.007743032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007085617,"threshold_uncertainty_score":0.003268123,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01375372850840236,"score_gpt":0.2704783897219052,"score_spread":0.2567246612135028,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}