{"id":"W2013427440","doi":"10.1007/s11912-010-0149-5","title":"Ramucirumab (IMC-1121B): Monoclonal Antibody Inhibition of Vascular Endothelial Growth Factor Receptor-2","year":2011,"lang":"en","type":"review","venue":"Current Oncology Reports","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Ramucirumab; Medicine; Angiogenesis; Cancer research; Monoclonal antibody; Vascular endothelial growth factor; Malignancy; Antibody; Immunology; Internal medicine; VEGF receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004177669,0.00105702,0.001142723,0.00111509,0.000159753,0.0006763909,0.0008298165,0.0008253633,0.001697292],"category_scores_gemma":[0.0003984474,0.0002315851,0.0003408224,0.0009410635,0.0002653024,0.0005612254,0.0003053885,0.00175421,0.001965133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006730045,"about_ca_system_score_gemma":0.0005844858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009818457,"about_ca_topic_score_gemma":0.002193954,"domain_scores_codex":[0.9998617,0.0000195067,0.00001473338,0.00002641042,0.00005639367,0.00002122228],"domain_scores_gemma":[0.9998945,0.00003893813,0.00002352236,0.000003216243,0.00002520608,0.0000146574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002054999,0.00010627,0.0001637769,0.002827044,0.00006930117,0.0003017132,0.0000147108,0.0003455764,0.003574139,0.001170395,0.03180601,0.9594156],"study_design_scores_gemma":[0.00021588,0.0003684696,0.001176776,0.000716528,0.0001954042,0.003592797,0.00001698737,0.000353366,0.003986592,0.000572735,0.9887791,0.0000253514],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008719119,0.994781,0.0005622195,0.0004949013,0.0005015573,0.00001686723,0.00004567801,0.00003879024,0.002687139],"genre_scores_gemma":[0.007810526,0.9849088,0.001087513,0.0008116063,0.0005065479,0.00003845649,0.0001784463,0.000007391676,0.004650585],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001697292,"threshold_uncertainty_score":0.005678058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07124718534146324,"score_gpt":0.3791760517233271,"score_spread":0.3079288663818639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}