{"id":"W2013433258","doi":"10.1002/stem.279","title":"Maximizing Functional Photoreceptor Differentiation From Adult Human Retinal Stem Cells","year":2009,"lang":"en","type":"article","venue":"Stem Cells","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Dalhousie University; Hospital for Sick Children; University of Toronto","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; Stem Cell Network; National Eye Institute; Lincy Foundation","keywords":"Biology; Retinal; Transducin; Cell biology; Stem cell; Retina; Transcription factor; Cellular differentiation; Visual phototransduction; Genetics; Gene; Neuroscience; Rhodopsin; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007077942,0.0002027039,0.000150604,0.00003988778,0.0001403141,0.00005331139,0.0001363034,0.0001540499,0.0002320951],"category_scores_gemma":[0.00000148322,0.0001966397,0.0001116048,0.00006094753,0.00002861019,0.00000682453,0.00004091085,0.00008911192,0.0001110563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002410607,"about_ca_system_score_gemma":0.00003313228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001625759,"about_ca_topic_score_gemma":0.00001303091,"domain_scores_codex":[0.9988043,0.00005236557,0.0002607344,0.0004125968,0.0002202204,0.0002498185],"domain_scores_gemma":[0.9995083,0.000008891298,0.0001232899,0.0001806476,0.00009268015,0.00008618033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001184162,0.00006007039,0.001910161,0.000009577219,0.00002898444,0.000001728931,0.00007198656,0.000006638826,0.9866421,0.00005077299,0.00799874,0.003100792],"study_design_scores_gemma":[0.0007248088,0.0001913143,0.01187244,0.00002590562,0.00002217633,0.000001078047,0.0001937921,0.0000436029,0.9787211,0.00009291725,0.007820466,0.0002904423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948073,0.0001941762,0.00140079,0.00006178873,0.0005672578,0.0001809162,0.00002582984,0.00002764134,0.002734293],"genre_scores_gemma":[0.9941099,0.00007349005,0.0002411739,0.0002917624,0.000277867,0.000009612267,0.0003326321,0.0000182033,0.004645417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009962278,"threshold_uncertainty_score":0.8018732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0100769694928295,"score_gpt":0.2047564186443678,"score_spread":0.1946794491515383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}