{"id":"W2013433258","doi":"10.1002/stem.279","title":"Maximizing Functional Photoreceptor Differentiation From Adult Human Retinal Stem Cells","year":2009,"lang":"en","type":"article","venue":"Stem Cells","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Dalhousie University; Hospital for Sick Children; University of Toronto","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; Stem Cell Network; National Eye Institute; Lincy Foundation","keywords":"Biology; Retinal; Transducin; Cell biology; Stem cell; Retina; Transcription factor; Cellular differentiation; Visual phototransduction; Genetics; Gene; Neuroscience; Rhodopsin; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003045015,0.0002856849,0.0002494503,0.0002247299,0.000116138,0.0003486958,0.0001194257,0.000204062,0.00152271],"category_scores_gemma":[0.0002548516,0.0001222135,0.0001630917,0.000150711,0.0001424846,0.0001332984,0.0003141443,0.000243662,0.0006486464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001435513,"about_ca_system_score_gemma":0.0002161266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002975193,"about_ca_topic_score_gemma":0.0007013371,"domain_scores_codex":[0.9998166,0.00002561206,0.0000201682,0.00003602388,0.00007726734,0.00002445528],"domain_scores_gemma":[0.9999022,0.00002312643,0.00001654983,0.00001506129,0.00002275265,0.00002018139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004782647,0.00001546972,0.0003211149,0.00003301803,0.000004214917,0.00004173015,0.00002393556,0.0001325798,0.9943873,0.0001693488,0.00009165966,0.004731867],"study_design_scores_gemma":[0.00001710893,0.0002152707,0.00226098,0.00001018156,0.00002143821,0.0002406994,0.0000210735,0.0007201211,0.9888758,0.00007933414,0.007533469,0.000004453925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9702539,0.003579625,0.01900824,0.0001432989,0.00003713563,0.0001242402,0.0003615085,0.000207707,0.006284196],"genre_scores_gemma":[0.984973,0.001714478,0.008331607,0.00006662899,0.00001790311,0.00005648417,0.0006081198,0.00005226528,0.004179553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00152271,"threshold_uncertainty_score":0.005093992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0100769694928295,"score_gpt":0.2047564186443678,"score_spread":0.1946794491515383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}