{"id":"W2013500571","doi":"10.1016/s0167-8140(01)00398-x","title":"Adenovirus-p53 gene therapy in human nasopharyngeal carcinoma xenografts","year":2001,"lang":"en","type":"article","venue":"Radiotherapy and Oncology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"Medical Research Council; Centre National d’Etudes Spatiales","keywords":"Nasopharyngeal carcinoma; Genetic enhancement; Cancer research; Transgene; Radiation therapy; Gene; Viral vector; Gene transfer; Vector (molecular biology); Carcinoma; Gene delivery; Biology; Medicine; Pathology; Internal medicine; Recombinant DNA; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006546149,0.0004502454,0.0007680023,0.0005098612,0.0004429992,0.0005694746,0.0004874808,0.0005843719,0.001710171],"category_scores_gemma":[0.0002961403,0.0003243743,0.0004357648,0.000424122,0.0004364313,0.0006798925,0.0001920048,0.0009036555,0.0003780873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007082225,"about_ca_system_score_gemma":0.0008490874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006833809,"about_ca_topic_score_gemma":0.004933657,"domain_scores_codex":[0.9996973,0.00006228346,0.00002556784,0.00005159444,0.00006120976,0.0001019506],"domain_scores_gemma":[0.9997403,0.0001172696,0.00002816284,0.00005285612,0.00002433747,0.00003716283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001281821,0.0004609341,0.0002828505,0.0001343853,0.00003366092,0.0001590919,0.0001731804,0.00109013,0.9902954,0.001978543,0.0002969196,0.003813183],"study_design_scores_gemma":[0.0001552113,0.001776227,0.001127401,0.00000933046,0.00004940687,0.0001844645,0.00005544653,0.00297381,0.9901229,0.0001368494,0.003401774,0.000007187899],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887559,0.002620226,0.003542552,0.00017509,0.0001833808,0.0001864004,0.001034146,0.0001417061,0.003360513],"genre_scores_gemma":[0.9911779,0.001389475,0.002257752,0.00002091796,0.00001856744,0.00009055985,0.000652137,0.00003264788,0.00436017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006833809,"threshold_uncertainty_score":0.01358807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02655763640163233,"score_gpt":0.3312168329632607,"score_spread":0.3046591965616284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}