{"id":"W2013560735","doi":"10.1021/ac403723t","title":"Real-Time Monitoring of Membrane-Protein Reconstitution by Isothermal Titration Calorimetry","year":2013,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Austrian Science Fund; University of Toronto; Deutsche Forschungsgemeinschaft","keywords":"Chemistry; Isothermal titration calorimetry; Titration; Calorimetry; Isothermal process; Membrane; Amperometric titration; Chromatography; Thermodynamics; Inorganic chemistry; Biochemistry; Organic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006569668,0.0001447796,0.0001664036,0.00001303622,0.0000380967,0.00001830604,0.0001340108,0.0002378522,0.0005259537],"category_scores_gemma":[0.00005167268,0.0001338068,0.00009902145,0.00007873987,0.0001209955,0.00001061658,0.0000334568,0.0001003784,0.00003924403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001666755,"about_ca_system_score_gemma":0.00005681382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009876744,"about_ca_topic_score_gemma":2.313474e-7,"domain_scores_codex":[0.9991274,0.00001571152,0.0002483161,0.0002693673,0.000144158,0.0001950039],"domain_scores_gemma":[0.9994509,0.00000747139,0.00007668146,0.000273802,0.00009398133,0.0000972007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000175988,0.00003752763,0.001539537,0.00004592652,0.00002998574,6.855676e-7,0.000003256279,0.000001882627,0.9972045,0.000009461251,0.0007370971,0.0003725562],"study_design_scores_gemma":[0.0002300265,0.00003387417,0.0005120907,0.00001793101,0.00003825097,0.000007262385,0.00001890163,0.00005892707,0.9983939,0.000009198852,0.0005277593,0.0001518927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883295,0.00002943472,0.00006555524,0.00004270199,0.00004503068,0.0001112448,0.00001736045,0.00001604651,0.01134316],"genre_scores_gemma":[0.9942138,0.00002168926,0.000459989,0.00001220069,0.0003812123,0.00001476335,0.0001681862,0.0000144524,0.004713744],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006629417,"threshold_uncertainty_score":0.5758824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007093430459349966,"score_gpt":0.2375557471478704,"score_spread":0.2304623166885205,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}