{"id":"W2013586134","doi":"10.1007/s10858-009-9359-2","title":"Approaches for the measurement of solvent exposure in proteins by 19F NMR","year":2009,"lang":"en","type":"article","venue":"Journal of Biomolecular NMR","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Ontario","keywords":"Chemistry; Fluorine-19 NMR; Solvent; Topology (electrical circuits); Paramagnetism; Calmodulin; Nuclear magnetic resonance spectroscopy; Chemical shift; Relaxation (psychology); Isotope; Chemical physics; Analytical Chemistry (journal); Calcium; Physical chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000668033,0.0001362451,0.0002048126,0.00005560495,0.00003744854,0.00001503767,0.0002961967,0.0001261056,0.000001502633],"category_scores_gemma":[0.00009589812,0.00009167159,0.0002277756,0.00009669911,0.00005017814,0.000004609376,0.00002847587,0.0001108204,1.360489e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002771781,"about_ca_system_score_gemma":0.0001139767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004580594,"about_ca_topic_score_gemma":0.00001062931,"domain_scores_codex":[0.9988723,0.0000460746,0.0004294786,0.0001446956,0.0003228103,0.0001846204],"domain_scores_gemma":[0.9991733,0.000006511471,0.000332882,0.0002496689,0.0001851639,0.00005247978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003093778,0.0001441215,0.00009170124,0.00002362359,0.0001030443,0.000005097423,0.00005314903,0.000373974,0.9820053,0.0001445894,0.0006281644,0.01611788],"study_design_scores_gemma":[0.001644506,0.002148307,0.0009849881,0.00006386304,0.0000673301,0.00005250834,0.000107462,0.0004464923,0.980893,0.001307142,0.01210489,0.0001795612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5173476,0.02851032,0.4498675,0.00225435,0.0001665227,0.001460953,0.00003905173,0.000004779094,0.0003489307],"genre_scores_gemma":[0.9960912,0.000147173,0.003398967,0.0001978175,0.0001150029,0.00001142546,0.000009408263,0.00001151788,0.00001747392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4787437,"threshold_uncertainty_score":0.3738259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01799543622902544,"score_gpt":0.2393266941375323,"score_spread":0.2213312579085068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}