{"id":"W2013599752","doi":"10.1371/journal.pgen.1002545","title":"Diced Triplets Expose Neurons to RISC","year":2012,"lang":"en","type":"letter","venue":"PLoS Genetics","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Biology; Myotonic dystrophy; RNA splicing; Trinucleotide repeat expansion; Genetics; Alternative splicing; RNA-binding protein; Gene; Exon; Phenotype; RNA; Cell biology; Allele","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006551826,0.0008215063,0.000614085,0.0003492729,0.0002346585,0.0001928028,0.001409385,0.0004814611,0.0007259845],"category_scores_gemma":[0.001013206,0.000830716,0.0002629037,0.0004847364,0.0001734101,0.0000616788,0.0005807038,0.001330516,0.004295589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006712259,"about_ca_system_score_gemma":0.0001707971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001410469,"about_ca_topic_score_gemma":0.000002029318,"domain_scores_codex":[0.994515,0.0007354554,0.0005980253,0.001499759,0.001308021,0.001343715],"domain_scores_gemma":[0.9968589,0.0004888432,0.0002593108,0.001727707,0.0001238569,0.0005413825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009358521,0.000128038,0.00008717064,0.00005632627,0.00001066546,0.0001665791,0.00008679776,0.00005589665,0.421876,0.000002956619,0.5773399,0.0001803104],"study_design_scores_gemma":[0.0001774823,0.0001462561,0.0001307724,0.00001954728,0.000128568,0.00001372076,0.000002333324,0.00007136941,0.5592866,0.00002907898,0.4394756,0.0005187075],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.6469396,0.0008496242,0.0001328589,0.3369159,0.004544714,0.003281355,0.001665571,0.0005161097,0.005154311],"genre_scores_gemma":[0.1042018,0.000130712,0.0004418377,0.8822818,0.006106402,0.0002656922,0.00008579044,0.0003734581,0.006112408],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.545366,"threshold_uncertainty_score":0.9994144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08376483668882194,"score_gpt":0.2778703759811272,"score_spread":0.1941055392923053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}