{"id":"W2013599752","doi":"10.1371/journal.pgen.1002545","title":"Diced Triplets Expose Neurons to RISC","year":2012,"lang":"en","type":"letter","venue":"PLoS Genetics","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Biology; Myotonic dystrophy; RNA splicing; Trinucleotide repeat expansion; Genetics; Alternative splicing; RNA-binding protein; Gene; Exon; Phenotype; RNA; Cell biology; Allele","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009592235,0.0006265127,0.0005854141,0.000404826,0.00167157,0.001658143,0.0008057968,0.01215936,0.01018101],"category_scores_gemma":[0.005421459,0.0004184804,0.0006906261,0.0002306773,0.001641852,0.001163661,0.0009395593,0.01110475,0.006053268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001487811,"about_ca_system_score_gemma":0.0004596101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005796904,"about_ca_topic_score_gemma":0.001012407,"domain_scores_codex":[0.9991745,0.0002094764,0.00008822115,0.0001275019,0.0002739356,0.0001262661],"domain_scores_gemma":[0.9983711,0.0009081064,0.0001149006,0.0001985965,0.0002053592,0.0002021197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006182669,0.0000947704,0.0009683508,0.0003048718,0.00007424496,0.01616842,0.0002633297,0.0004926281,0.02780884,0.02039454,0.8817331,0.05107865],"study_design_scores_gemma":[0.0003175445,0.0003238285,0.00186706,0.0001648878,0.00004279874,0.02006158,0.0002343904,0.001480128,0.03484997,0.03565964,0.9049113,0.00008685399],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01626365,0.01531656,0.005839,0.8488022,0.07184151,0.00007951181,0.0003959023,0.0008287834,0.04063288],"genre_scores_gemma":[0.2384786,0.01837833,0.006320527,0.5552459,0.06741324,0.0002398517,0.0004608858,0.0002662792,0.1131963],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01215936,"threshold_uncertainty_score":0.03405887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08376483668882194,"score_gpt":0.2778703759811272,"score_spread":0.1941055392923053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}