{"id":"W2013623022","doi":"10.1371/journal.pone.0092941","title":"Gene Splicing of an Invertebrate Beta Subunit (LCavβ) in the N-Terminal and HOOK Domains and Its Regulation of LCav1 and LCav2 Calcium Channels","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Biotechnology and Biological Sciences Research Council; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Biology; Alternative splicing; Exon; Gene isoform; Protein subunit; Lymnaea stagnalis; Calcium channel; Voltage-dependent calcium channel; R-type calcium channel; Drosophila melanogaster; Cell biology; L-type calcium channel; Genetics; Gene; Snail; Calcium; T-type calcium channel; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006761977,0.0001568193,0.00007915306,0.00009857144,0.0001008446,0.0001981755,0.00009380384,0.000113693,0.0004354442],"category_scores_gemma":[0.00008871531,0.0000881161,0.0001467812,0.0000603868,0.0001734591,0.00007033216,0.0001900984,0.0002518943,0.0001681338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002173271,"about_ca_system_score_gemma":0.0001214475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007429492,"about_ca_topic_score_gemma":0.001292335,"domain_scores_codex":[0.9999101,0.000009793227,0.000006714861,0.0000312071,0.0000222225,0.00002002919],"domain_scores_gemma":[0.9999129,0.00001000193,0.0000366425,0.00000860293,0.00001425488,0.0000176452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003179962,0.000006222225,0.001032351,0.00000525434,0.000001916689,0.00004635659,0.0000179456,0.00003181023,0.9981192,0.0001130989,0.00001217114,0.0005819525],"study_design_scores_gemma":[0.00002907534,0.0002687831,0.1254564,0.00001453062,0.00003448869,0.001309717,0.0002133021,0.003613602,0.8642299,0.000241428,0.004575932,0.00001279436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982439,0.0002501632,0.0008904749,0.00001406529,0.000007671861,0.000004662147,0.00006929816,0.00001691444,0.0005028449],"genre_scores_gemma":[0.997889,0.0001436616,0.0007656619,0.00003187759,0.000003541465,0.0000115697,0.0002060518,0.00001203129,0.0009365357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007429492,"threshold_uncertainty_score":0.0015769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03360806359625366,"score_gpt":0.2352513656977609,"score_spread":0.2016433021015073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}