{"id":"W2013772831","doi":"10.1016/j.molimm.2007.06.094","title":"AR36A36.11.1, a monoclonal antibody targeting CD59, enhances complement activity and exhibits potent in vivo efficacy in multiple human cancer models","year":2007,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Arius3D (Canada)","funders":"","keywords":"In vivo; Monoclonal antibody; CD59; Complement (music); Cancer research; Cancer; Complement system; Antibody; Chemistry; Immunology; Medicine; Biology; Internal medicine; Biochemistry; Gene; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009257784,0.0002496869,0.0003978798,0.0002566583,0.0001330929,0.00004072574,0.0002566444,0.000120297,0.00009547331],"category_scores_gemma":[0.0000626789,0.0002624084,0.00005089144,0.0002598337,0.000221243,0.0002162748,0.0002773345,0.0002133783,0.00001052617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002256255,"about_ca_system_score_gemma":0.00006682393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005786853,"about_ca_topic_score_gemma":0.003854813,"domain_scores_codex":[0.9975685,0.0002738766,0.0005151089,0.0006039665,0.0002414223,0.0007971666],"domain_scores_gemma":[0.9992679,0.00015149,0.0001667432,0.0002848781,0.0000581878,0.00007074657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002053736,0.0004436506,0.005015382,0.00001688078,0.00001348061,0.0002068435,0.0004415514,0.004494156,0.9880865,0.0002832213,0.000005922594,0.0007870703],"study_design_scores_gemma":[0.002140085,0.0001064199,0.02969871,0.00006222088,0.000008742805,0.00000729204,0.000121076,0.003775096,0.9635788,0.0001844972,0.00004924093,0.0002678382],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940305,0.001511349,0.00349968,0.0001892299,0.000180985,0.0004756738,0.00001859036,0.00005001625,0.00004401399],"genre_scores_gemma":[0.9985715,0.00004740834,0.001155156,0.0001149324,0.00002093235,0.00004780177,0.0000086182,0.00002495407,0.000008763575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02468333,"threshold_uncertainty_score":0.9999828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02011677403304479,"score_gpt":0.2937173116670337,"score_spread":0.2736005376339889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}