{"id":"W2013964647","doi":"10.1074/jbc.m600514200","title":"Transforming Growth Factor-β Stimulates Cyclin D1 Expression through Activation of β-Catenin Signaling in Chondrocytes","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; University of Toronto; Canadian Institute for Theoretical Astrophysics","keywords":"Cyclin D1; Cell biology; Cyclin D; Transforming growth factor; Signal transduction; Chemistry; Cancer research; Expression (computer science); Catenin; Cyclin; Wnt signaling pathway; Biology; Cell cycle; Apoptosis; Biochemistry; Computer science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001451602,0.0001498474,0.0002566699,0.00003185579,0.00002898485,0.000009737822,0.0001463914,0.0003728503,0.00004173287],"category_scores_gemma":[0.0001240882,0.0001150171,0.0001566841,0.0001184286,0.00006657208,0.00001875816,0.0000261953,0.0001963802,2.956668e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004946649,"about_ca_system_score_gemma":0.00005232909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001708669,"about_ca_topic_score_gemma":0.000001081554,"domain_scores_codex":[0.9988387,0.00003634598,0.0006188752,0.0001841156,0.0001537534,0.0001682761],"domain_scores_gemma":[0.9992283,0.00004790284,0.0004462398,0.0000858588,0.0001562394,0.00003546315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003040374,0.0000887855,0.006054046,0.00003555038,0.00001639084,0.000001990845,0.0000269201,0.0042329,0.9888146,0.000002003518,0.00004216278,0.0003806194],"study_design_scores_gemma":[0.0007949686,0.0001445479,0.004034065,0.0001399721,0.000008363425,0.00002075618,0.00004651376,0.00004639947,0.9940274,0.0004035025,0.0002015442,0.0001320052],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965289,0.0008395654,0.002288957,0.00005574812,0.00005518322,0.00007227009,0.000007429806,0.000004926793,0.0001469671],"genre_scores_gemma":[0.9983467,0.0001870784,0.001016568,0.00001057629,0.0003365345,0.000002208923,0.00005764361,0.00001026261,0.00003239388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005212769,"threshold_uncertainty_score":0.4690259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0169442059662599,"score_gpt":0.2581769756612909,"score_spread":0.241232769695031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}