{"id":"W2013975403","doi":"10.1111/j.1471-4159.2009.06153.x","title":"Hypoxia inducible factor (HIF)‐2α is required for the development of the catecholaminergic phenotype of sympathoadrenal cells","year":2009,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research; McMaster University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Tyrosine hydroxylase; Catecholaminergic; Endocrinology; Internal medicine; Biology; Catecholamine; Hypoxia-inducible factors; Chromaffin cell; Dopamine; Transcription factor; Sympathoadrenal system; Hypoxia (environmental); Adrenal medulla; Catecholaminergic cell groups; Tyrosine 3-Monooxygenase; Cell biology; Chemistry; Gene; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006509518,0.0001513865,0.0001842928,0.00009267803,0.0001263755,0.0002502934,0.0001061836,0.0001158591,0.0005700089],"category_scores_gemma":[0.00008182392,0.000110779,0.000147543,0.00008491083,0.0001302987,0.00009485337,0.000150708,0.0002323532,0.0002637855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001957891,"about_ca_system_score_gemma":0.0001480914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000800492,"about_ca_topic_score_gemma":0.001065734,"domain_scores_codex":[0.9999216,0.00001019917,0.000006842632,0.00001702218,0.00002362817,0.00002084927],"domain_scores_gemma":[0.9998808,0.00001040915,0.00003753756,0.00001049679,0.00001317988,0.00004756551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003091313,0.000004060117,0.0003605065,0.0000096618,0.000002266127,0.00004195542,0.000007611225,0.00001017087,0.9990796,0.00002939547,0.00002047021,0.0004033157],"study_design_scores_gemma":[0.00001774722,0.0001841381,0.1544409,0.00001262415,0.00002099442,0.001034416,0.00009402982,0.00108019,0.8358754,0.00008647626,0.007145122,0.000008012782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993857,0.001909579,0.002576001,0.00006721244,0.00003298164,0.00001102123,0.0003908523,0.00005516694,0.001100148],"genre_scores_gemma":[0.9961999,0.0007357575,0.0007878758,0.0000313333,0.00001396039,0.00001317833,0.0007427699,0.00001246343,0.001462686],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000800492,"threshold_uncertainty_score":0.001906812,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01956674370770693,"score_gpt":0.2561803465912865,"score_spread":0.2366136028835796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}