{"id":"W2013981603","doi":"10.1038/ng1413","title":"Abnormal TNF activity in Timp3−/− mice leads to chronic hepatic inflammation and failure of liver regeneration","year":2004,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":283,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Tumor necrosis factor alpha; Biology; Inflammation; Hepatocyte; Cytokine; Liver regeneration; Liver injury; Immunology; Necrosis; Endocrinology; Internal medicine; Regeneration (biology); Medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004108977,0.0009956093,0.0005165642,0.001751699,0.0004501776,0.0008805593,0.0005456635,0.001058245,0.005444393],"category_scores_gemma":[0.0004144605,0.000647211,0.0006434973,0.0006008447,0.001013439,0.0005873213,0.0003559718,0.002655294,0.00166957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004768394,"about_ca_system_score_gemma":0.0002952655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005832546,"about_ca_topic_score_gemma":0.0006995965,"domain_scores_codex":[0.9994035,0.0001036877,0.0001144214,0.0001185501,0.0001461072,0.0001137948],"domain_scores_gemma":[0.9985759,0.000158094,0.0006073596,0.0001447793,0.00005799089,0.0004558866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004601675,0.00004151416,0.000230596,0.00002429642,0.000009573165,0.0001874752,0.0000194179,0.00003468697,0.9983835,0.0001601647,0.00004236583,0.0004062374],"study_design_scores_gemma":[0.0001199254,0.0004113677,0.004921389,0.00001528876,0.00005703184,0.002452026,0.000130072,0.0006132548,0.9898602,0.000279064,0.001123472,0.00001698319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907936,0.0009344487,0.004305642,0.0004951497,0.0001120906,0.00003311218,0.001375402,0.0004062144,0.001544313],"genre_scores_gemma":[0.9887435,0.0007677445,0.003126218,0.0001528629,0.00005611041,0.00006630288,0.0007648108,0.0003004315,0.006021919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005444393,"threshold_uncertainty_score":0.01821327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008781912366857724,"score_gpt":0.2582568583837505,"score_spread":0.2494749460168928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}