{"id":"W2013998513","doi":"10.1016/j.jphotobiol.2011.11.002","title":"Evaluation of solute binding to proteins and intra-protein distances from steady state fluorescence measurements","year":2011,"lang":"en","type":"review","venue":"Journal of Photochemistry and Photobiology B Biology","topic":"Protein Interaction Studies and Fluorescence Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Departamento de Investigaciones Científicas y Tecnológicas, Universidad de Santiago de Chile","keywords":"Covalent bond; Chemistry; Steady state (chemistry); Fluorescence; Bovine serum albumin; Biophysics; Serum albumin; Plasma protein binding; Human serum albumin; Chromatography; Biochemistry; Biology; Organic chemistry; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001147985,0.001618132,0.001970119,0.001729194,0.000207477,0.0007003433,0.001669973,0.001299088,0.001201262],"category_scores_gemma":[0.001128756,0.0006450942,0.0005159714,0.00192216,0.001004024,0.001576354,0.0005392699,0.001408075,0.001798504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000872689,"about_ca_system_score_gemma":0.0004796716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009119066,"about_ca_topic_score_gemma":0.001460625,"domain_scores_codex":[0.9994722,0.00006771943,0.0000277187,0.0001793007,0.0002265147,0.00002651612],"domain_scores_gemma":[0.9992569,0.0004365819,0.00008034125,0.00003774139,0.0001718636,0.00001652901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001337254,0.00009517842,0.0004109644,0.007515409,0.00008447416,0.0001557153,0.00005169449,0.001194553,0.1539004,0.005319448,0.006874237,0.8242642],"study_design_scores_gemma":[0.00004288929,0.0004358276,0.007162402,0.001682334,0.0004848977,0.003767576,0.0001754978,0.006179605,0.5187997,0.01125537,0.4497719,0.0002419225],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005087417,0.9459416,0.04195487,0.0003734273,0.0005547996,0.00004254841,0.0002755317,0.0001808474,0.005589041],"genre_scores_gemma":[0.02994013,0.9247174,0.03329916,0.0003988457,0.0003489259,0.0001362929,0.000442579,0.00008079969,0.01063591],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001970119,"threshold_uncertainty_score":0.006331801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08983788890877484,"score_gpt":0.3587604120426671,"score_spread":0.2689225231338923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}