{"id":"W2014016939","doi":"10.1016/j.antiviral.2011.06.003","title":"Minigenomes, transcription and replication competent virus-like particles and beyond: Reverse genetics systems for filoviruses and other negative stranded hemorrhagic fever viruses","year":2011,"lang":"en","type":"review","venue":"Antiviral Research","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":134,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Virology; Reverse genetics; Viral replication; Virus; Transcription (linguistics); Viral life cycle; Marburg virus; Reverse transcriptase; Genome; Genetics; RNA; Computational biology; Ebola virus; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001629713,0.0003735958,0.001109376,0.00050129,0.0003929315,0.0002020738,0.0001194676,0.0003332142,0.00002178838],"category_scores_gemma":[0.0002160433,0.0002853445,0.0001674568,0.0004091969,0.0006732108,0.000169384,0.0001115856,0.0005959925,0.00002425609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009635161,"about_ca_system_score_gemma":0.0002476303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001137175,"about_ca_topic_score_gemma":0.0002053857,"domain_scores_codex":[0.9968987,0.0005762346,0.0005890562,0.0008852261,0.0004444841,0.000606373],"domain_scores_gemma":[0.998141,0.0006360401,0.0001439868,0.0005152887,0.0003501653,0.0002135046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005353532,0.0003590603,0.000706876,0.02178835,0.0005556955,0.00002667753,0.0008913432,7.104821e-8,0.006515982,0.0009120048,0.00255367,0.9651549],"study_design_scores_gemma":[0.001513611,0.001315244,0.0004241345,0.00271996,0.0006315965,0.0001333336,0.000528626,0.0002586324,0.001154008,0.0002752673,0.9906234,0.0004221691],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02566347,0.9689815,0.00007299529,0.00006558365,0.00008299592,0.004193433,0.0004526179,0.00004018228,0.0004472215],"genre_scores_gemma":[0.01681028,0.980814,0.0003819226,0.0001013794,0.0001530655,0.0004913942,0.00004632602,0.00008249714,0.001119076],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9880698,"threshold_uncertainty_score":0.9999599,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3154312292024623,"score_gpt":0.4561723369112449,"score_spread":0.1407411077087826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}