{"id":"W2014023656","doi":"10.1016/s0142-9612(03)00539-8","title":"Nanotexturing of titanium-based surfaces upregulates expression of bone sialoprotein and osteopontin by cultured osteogenic cells","year":2003,"lang":"en","type":"article","venue":"Biomaterials","topic":"Bone and Dental Protein Studies","field":"Medicine","cited_by":360,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; Universidade de São Paulo; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Bone sialoprotein; Osteopontin; Calvaria; Fibronectin; Materials science; Osteoid; Titanium; Immunogold labelling; Molecular biology; Nanotopography; Type I collagen; Immunolabeling; Biophysics; Cell biology; Chemistry; Extracellular matrix; Biology; Alkaline phosphatase; Pathology; Antibody; Osteocalcin; Anatomy; Immunology; Nanotechnology; Biochemistry; Medicine; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001315861,0.0003105649,0.0002757964,0.0001822945,0.0002108417,0.0003462203,0.0002076579,0.0003541489,0.001032544],"category_scores_gemma":[0.0002110573,0.0002369943,0.0004721797,0.0001903188,0.0002231717,0.0002513368,0.0002735221,0.0003673176,0.0002547615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002614529,"about_ca_system_score_gemma":0.0001844978,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009382608,"about_ca_topic_score_gemma":0.001676147,"domain_scores_codex":[0.9998337,0.00001614976,0.00001255589,0.00002410079,0.00005204331,0.00006142848],"domain_scores_gemma":[0.9998735,0.00005091574,0.00002111762,0.00002046954,0.00001575636,0.00001828621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007492901,0.00001863621,0.0001280531,0.00001049454,0.000003937337,0.00006220565,0.00002010233,0.00005591058,0.999115,0.00002603947,0.00001017143,0.0004745553],"study_design_scores_gemma":[0.00000826446,0.0001280751,0.002810368,0.000002118946,0.00001038618,0.00006368336,0.00004253574,0.0005140911,0.9960411,0.00002476345,0.0003513164,0.000003319022],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972708,0.0005147228,0.0009356708,0.00002603516,0.00003290651,0.00001239253,0.00006624906,0.00001115482,0.001129958],"genre_scores_gemma":[0.9957802,0.0003469166,0.001265859,0.00004873293,0.00001554514,0.00002761165,0.0001920291,0.00001241548,0.002310785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001032544,"threshold_uncertainty_score":0.003454149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007934180094394385,"score_gpt":0.2235968970823285,"score_spread":0.2156627169879342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}