{"id":"W2014036889","doi":"10.1007/s11538-009-9469-8","title":"Dynamics of Notch Activity in a Model of Interacting Signaling Pathways","year":2010,"lang":"en","type":"article","venue":"Bulletin of Mathematical Biology","topic":"Gene Regulatory Network Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University","funders":"","keywords":"Notch signaling pathway; Hes3 signaling axis; Hopf bifurcation; Signal transduction; Dynamics (music); Bifurcation; Retinoic acid; Biology; Physics; Biological system; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006988837,0.0007162048,0.00158214,0.001092443,0.0009312366,0.002214303,0.001750492,0.002035978,0.003910834],"category_scores_gemma":[0.003449305,0.0005889463,0.0008965147,0.0008768979,0.001683004,0.001951591,0.001034021,0.00108586,0.0002801105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002042231,"about_ca_system_score_gemma":0.001137251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008332401,"about_ca_topic_score_gemma":0.005208434,"domain_scores_codex":[0.9996568,0.0001401856,0.00001231992,0.00005949467,0.00006585698,0.00006535545],"domain_scores_gemma":[0.9981413,0.001096866,0.0002836874,0.00006777039,0.000164961,0.0002455442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001641747,0.00007996539,0.001125613,0.00004942133,0.00005799298,0.0002274284,0.0000951951,0.8016592,0.003136339,0.1909297,0.0007548899,0.001720285],"study_design_scores_gemma":[0.00001609949,0.00001197687,0.0001576398,0.000002544029,0.000009292615,0.00002016932,0.00001411215,0.9868013,0.00009009482,0.01276974,0.0001001129,0.000007015993],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.767642,0.0006459727,0.1999121,0.002451219,0.00009589183,0.00005874303,0.0004926986,0.000270434,0.02843098],"genre_scores_gemma":[0.9846087,0.0003222609,0.005756598,0.00007793948,0.00003697007,0.00006370316,0.0001244916,0.00003619009,0.008973162],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008332401,"threshold_uncertainty_score":0.01656783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01368615070733646,"score_gpt":0.2476790226944498,"score_spread":0.2339928719871134,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}