{"id":"W2014057800","doi":"10.1016/s0002-9440(10)61120-0","title":"Adenoviral Transfer of Murine Oncostatin M Elicits Periosteal Bone Apposition in Knee Joints of Mice, Despite Synovial Inflammation and Up-Regulated Expression of Interleukin-6 and Receptor Activator of Nuclear Factor-κB Ligand","year":2002,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Dutch Arthritis Association","keywords":"Oncostatin M; Osteoprotegerin; Osteoclast; Osteoblast; RANKL; Bone resorption; Chemistry; Internal medicine; Endocrinology; Periosteum; Cell biology; Receptor; Biology; Cytokine; Activator (genetics); Interleukin 6; Medicine; Anatomy; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001126186,0.0001109539,0.0004528195,0.0001616652,0.00001206167,0.000002634083,0.00005832955,0.0000803229,0.00001898208],"category_scores_gemma":[0.00007134729,0.00009809047,0.00006581559,0.00009687537,0.000362337,0.0000196652,0.00003490036,0.00008463425,1.047581e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005936734,"about_ca_system_score_gemma":0.0000253393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002068385,"about_ca_topic_score_gemma":0.000003632951,"domain_scores_codex":[0.9989033,0.0001629607,0.0005956845,0.0001267012,0.0001091162,0.0001022257],"domain_scores_gemma":[0.9991438,0.00002425056,0.0005416605,0.00009135568,0.0001379967,0.00006093601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001421931,0.0001189238,0.004447884,0.00006987803,0.00002485857,0.000006230639,0.00170463,0.000005925687,0.9763675,0.000005793485,0.00001125749,0.0158152],"study_design_scores_gemma":[0.001758602,0.002376209,0.08039728,0.0001393863,0.00003756987,0.00008495509,0.000793412,0.00001230788,0.9142763,0.00000763666,0.00003579474,0.00008052525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990283,0.000634928,0.00009674241,0.0000363563,0.00004049256,0.00008774508,0.00006541749,0.000001121028,0.000008936589],"genre_scores_gemma":[0.9988518,0.0004343627,0.0006378258,0.00001344132,0.00003615638,9.501408e-7,0.00000944092,0.00001203173,0.000003986524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07594939,"threshold_uncertainty_score":0.4000013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006068723124926659,"score_gpt":0.2161498584434385,"score_spread":0.2100811353185118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}