{"id":"W2014057800","doi":"10.1016/s0002-9440(10)61120-0","title":"Adenoviral Transfer of Murine Oncostatin M Elicits Periosteal Bone Apposition in Knee Joints of Mice, Despite Synovial Inflammation and Up-Regulated Expression of Interleukin-6 and Receptor Activator of Nuclear Factor-κB Ligand","year":2002,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Dutch Arthritis Association","keywords":"Oncostatin M; Osteoprotegerin; Osteoclast; Osteoblast; RANKL; Bone resorption; Chemistry; Internal medicine; Endocrinology; Periosteum; Cell biology; Receptor; Biology; Cytokine; Activator (genetics); Interleukin 6; Medicine; Anatomy; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002923058,0.000850331,0.0004056676,0.0008533323,0.0002943366,0.0005698213,0.0003358875,0.0008478368,0.002213702],"category_scores_gemma":[0.0001677058,0.0005487101,0.0006551145,0.0003484162,0.0007164102,0.0004116948,0.0003950628,0.001809876,0.0007666415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005021603,"about_ca_system_score_gemma":0.0004332552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001113586,"about_ca_topic_score_gemma":0.002340988,"domain_scores_codex":[0.9994072,0.00006290618,0.00005359158,0.0001098201,0.000145437,0.0002210546],"domain_scores_gemma":[0.9994923,0.00005533634,0.0001924331,0.00005473246,0.00001938901,0.0001857628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002432672,0.00004452616,0.00007737002,0.00001879505,0.000004773063,0.00007139838,0.00001395039,0.00002733222,0.9991357,0.0001147366,0.00002797012,0.0002202623],"study_design_scores_gemma":[0.00009383672,0.0008841779,0.004771527,0.00001250012,0.00004412368,0.000482847,0.0001195214,0.0007224468,0.9908432,0.0001174919,0.00189867,0.00000970473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921271,0.001374517,0.002392354,0.0003132574,0.0001679335,0.00006424593,0.001100636,0.0001787271,0.002281158],"genre_scores_gemma":[0.9907779,0.0007004215,0.00142651,0.0001025519,0.00003134987,0.00004856448,0.0007193465,0.00004323346,0.006150172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002213702,"threshold_uncertainty_score":0.007405639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006068723124926659,"score_gpt":0.2161498584434385,"score_spread":0.2100811353185118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}