{"id":"W2014064665","doi":"10.1016/j.ab.2009.02.031","title":"Development of a homogeneous immunoassay for the detection of angiotensin I in plasma using AlphaLISA acceptor beads technology","year":2009,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Pharmacological Effects and Assays","field":"Agricultural and Biological Sciences","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Immunoassay; Chemistry; Chromatography; Renin–angiotensin system; Radioimmunoassay; Angiotensin II; Plasma renin activity; Detection limit; Substrate (aquarium); Homogeneous; Antibody; Receptor; Biochemistry; Endocrinology; Medicine; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002093607,0.00009775528,0.0001913445,0.0000144987,0.00007177525,0.00000740766,0.0002002393,0.0001568622,0.00003120843],"category_scores_gemma":[0.000124509,0.00003558689,0.0000937372,0.0003951163,0.0001036536,0.00001675818,0.00004154748,0.00009048176,5.129414e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004873057,"about_ca_system_score_gemma":0.00001617367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001788378,"about_ca_topic_score_gemma":0.00001325365,"domain_scores_codex":[0.9992424,0.00001324995,0.0002745332,0.0001724895,0.0001038299,0.0001934943],"domain_scores_gemma":[0.9995415,0.0002186752,0.00009382969,0.00004905949,0.00006325076,0.00003373438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000046139,0.00009750154,0.0001163594,0.000004584882,0.00001654417,0.00000109525,0.000005240865,0.00000966208,0.8587239,0.00002054973,0.000008148601,0.1409503],"study_design_scores_gemma":[0.0001586912,0.0001213965,0.002644385,0.00001655541,0.00002546282,0.000004769105,0.00008371092,0.004192344,0.9921771,0.00007252017,0.0004185185,0.00008455425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988425,0.0002114489,0.0001172047,0.0005876992,0.00001956291,0.0001415687,0.0000111176,0.00001262459,0.00005630885],"genre_scores_gemma":[0.9991316,0.000008653446,0.0007366649,0.00005515213,0.00004197199,0.000005787158,0.00000687633,5.112431e-7,0.00001275548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1408657,"threshold_uncertainty_score":0.1451191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02350521398603428,"score_gpt":0.2717461919353086,"score_spread":0.2482409779492744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}