{"id":"W2014078475","doi":"10.1021/bi051951y","title":"Crystal Structure of Homoserine Transacetylase from <i>Haemophilus influenzae</i> Reveals a New Family of α/β-Hydrolases<sup>,</sup>","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Hydrolase; Chemistry; Homoserine; Active site; Enzyme; Hydrolysis; Haemophilus influenzae; Stereochemistry; Biochemistry; Quorum sensing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00005129178,0.0002493444,0.0005965823,0.00007178845,0.00002770553,0.000007915853,0.0001434095,0.000237057,0.001052103],"category_scores_gemma":[0.00007699071,0.0002341183,0.0003287103,0.0003060566,0.0001298921,0.00006242264,0.00002899886,0.0002182058,0.000008821675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004946849,"about_ca_system_score_gemma":0.0002084601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001807257,"about_ca_topic_score_gemma":0.000006307376,"domain_scores_codex":[0.9984052,0.00001863133,0.0006199923,0.0003417894,0.0003867513,0.0002276708],"domain_scores_gemma":[0.9987823,0.00003697108,0.0002116867,0.0005379657,0.0001264458,0.0003046556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002332881,0.0001707801,0.0005852535,0.0002379977,0.0001630693,0.00001869505,0.0002013811,0.0002006155,0.9928347,0.000003677671,0.00448604,0.0008645289],"study_design_scores_gemma":[0.002862786,0.00007862471,0.0006185204,0.0006402444,0.0002505293,0.00004044614,0.0002038644,0.000642404,0.9934099,0.00008385493,0.0009652354,0.0002035763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966516,0.0008188844,0.0001154273,0.0004962987,0.000006464707,0.0001124109,0.001049142,0.00004682847,0.0007029155],"genre_scores_gemma":[0.9952494,0.0000367999,0.002016092,0.0008109031,0.0004328187,0.000001951553,0.0003601987,0.00002601405,0.001065817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003520805,"threshold_uncertainty_score":0.9998611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009186562030623917,"score_gpt":0.2388751333603771,"score_spread":0.2296885713297532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}