{"id":"W2014117711","doi":"10.1046/j.0306-5251.2001.01565.x","title":"Sex and age differences in the pharmacokinetics of alosetron","year":2002,"lang":"en","type":"article","venue":"British Journal of Clinical Pharmacology","topic":"Nausea and vomiting management","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"GlaxoSmithKline (Canada)","funders":"","keywords":"Medicine; Pharmacokinetics; Statistical significance; Internal medicine; Volume of distribution; Physiology; Significant difference; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001679241,0.00007125662,0.0005826738,0.00007743102,0.0000236091,0.00001266611,0.0001655891,0.00006632477,0.0003827554],"category_scores_gemma":[0.0003293117,0.0000554813,0.0001227961,0.0001047624,0.0002425758,0.00003978497,0.00004090083,0.000632933,0.000002078235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007311852,"about_ca_system_score_gemma":0.00001541037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001019242,"about_ca_topic_score_gemma":0.00000353064,"domain_scores_codex":[0.9980497,0.0004370068,0.001018369,0.0001069569,0.0002302582,0.0001576545],"domain_scores_gemma":[0.9984671,0.000922245,0.000387873,0.00005277693,0.00006923471,0.0001007483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0006854329,0.003890152,0.3386854,0.0002716032,0.0006386872,0.01318674,0.0005256569,0.000006382427,0.002927223,0.00005784586,0.1939009,0.445224],"study_design_scores_gemma":[0.01619848,0.002279023,0.9484176,0.0002583263,0.0007590711,0.002955711,0.0002441528,0.0006377994,0.0004235423,0.000316923,0.02737919,0.0001301673],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920435,0.0024755,0.00001947458,0.002947467,0.0005281694,0.0001591678,0.000002690518,0.000003327236,0.001820693],"genre_scores_gemma":[0.9840124,0.01176402,0.0002035644,0.003013687,0.0007654288,0.000001615224,4.853086e-7,0.000006190896,0.0002326309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6097322,"threshold_uncertainty_score":0.4190903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1276042135431599,"score_gpt":0.4215711812638643,"score_spread":0.2939669677207045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}