{"id":"W2014183823","doi":"10.1159/000213748","title":"DEFECT OF PROTEOLYSIS OF MITOCHONDRIAL ATP SYNTHASE SUBUNIT C IN NEURONAL CEROID LIPOFUSCINOSIS","year":2009,"lang":"en","type":"article","venue":"Gerontology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Neuronal ceroid lipofuscinosis; Protein subunit; ATP synthase; Proteolysis; Mitochondrion; Lysosome; Biology; Biochemistry; Autophagy; Molecular biology; Cell biology; Chemistry; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001258782,0.0001634634,0.0003916818,0.0001439653,0.00002099462,0.000002764441,0.000200079,0.0002694667,0.0001628733],"category_scores_gemma":[0.0002469976,0.0001632198,0.0002020107,0.0001533746,0.0001363459,0.000003972812,0.0000463198,0.0001257189,0.000007679945],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001002547,"about_ca_system_score_gemma":0.00007681407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009326005,"about_ca_topic_score_gemma":0.0003598242,"domain_scores_codex":[0.9985558,0.000230568,0.0004465044,0.0003852521,0.0001071107,0.00027476],"domain_scores_gemma":[0.9992196,0.00003688144,0.0001942023,0.0003994915,0.00008605058,0.00006379701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009803047,0.0002024224,0.005158134,0.00001431802,0.00002898271,0.000007632311,0.00008942899,0.00003613898,0.9892057,0.0001622631,0.001455712,0.002658964],"study_design_scores_gemma":[0.003230878,0.004067613,0.02863549,0.00002339804,0.00007735031,0.0000894311,0.00006560609,0.00003809688,0.9408433,0.0002001953,0.02237998,0.0003486494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955022,0.0003924309,0.001559039,0.0005249685,0.0005279901,0.0003005743,0.00002236124,0.000008684749,0.001161783],"genre_scores_gemma":[0.9970919,0.00006137574,0.00189462,0.0005165262,0.0001704628,0.00002424119,0.00005674228,0.00001136691,0.0001727007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04836239,"threshold_uncertainty_score":0.6655909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01910765555643468,"score_gpt":0.2639945424565358,"score_spread":0.2448868869001011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}