{"id":"W2014183823","doi":"10.1159/000213748","title":"DEFECT OF PROTEOLYSIS OF MITOCHONDRIAL ATP SYNTHASE SUBUNIT C IN NEURONAL CEROID LIPOFUSCINOSIS","year":2009,"lang":"en","type":"article","venue":"Gerontology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Neuronal ceroid lipofuscinosis; Protein subunit; ATP synthase; Proteolysis; Mitochondrion; Lysosome; Biology; Biochemistry; Autophagy; Molecular biology; Cell biology; Chemistry; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000192866,0.0003794296,0.0002511025,0.000510525,0.0002172561,0.0002227451,0.0001851451,0.0003821758,0.0006776493],"category_scores_gemma":[0.0004355143,0.0001370178,0.0001288541,0.0001622395,0.0003996234,0.0002529156,0.0001758235,0.0002140069,0.0002792115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003463107,"about_ca_system_score_gemma":0.000212098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005747826,"about_ca_topic_score_gemma":0.0004538692,"domain_scores_codex":[0.9999061,0.00002246843,0.00001834145,0.00002089379,0.00001984151,0.00001242176],"domain_scores_gemma":[0.9997831,0.00005435145,0.00007010255,0.00002717283,0.00002546716,0.00003980371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000566682,0.00005159076,0.008754739,0.00006307169,0.00001426465,0.008246468,0.0001240877,0.0001654723,0.9775475,0.0003199647,0.00007986395,0.004066349],"study_design_scores_gemma":[0.00006461976,0.001032288,0.1200526,0.00002561531,0.0001022773,0.09320445,0.000355633,0.002867757,0.7785725,0.0005838692,0.003108402,0.0000299645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980052,0.0006065495,0.0008852415,0.00002663346,0.000004985292,0.000006516647,0.00005823866,0.00002648807,0.0003801482],"genre_scores_gemma":[0.9987957,0.0003221226,0.0004471064,0.000008807453,0.000002754154,0.000008028788,0.00008017912,0.000005853621,0.0003293677],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006776493,"threshold_uncertainty_score":0.002512753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01910765555643468,"score_gpt":0.2639945424565358,"score_spread":0.2448868869001011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}