{"id":"W2014185236","doi":"10.1523/jneurosci.3600-07.2007","title":"An Ion Channel Essential for Sensing Chemical Damage","year":2007,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":288,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Neurological Disorders and Stroke; Fondation pour la Recherche Médicale","keywords":"Iodoacetamide; Ion channel; Cysteine; Chemistry; Oxidative stress; Formaldehyde; In vitro; Biophysics; Biochemistry; Cell biology; Biology; Receptor; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012891,0.0003793928,0.0005066987,0.0002169996,0.0003358886,0.0005569182,0.0005529565,0.0009403241,0.001217897],"category_scores_gemma":[0.0003618757,0.0001683351,0.0003574138,0.0001390366,0.0004303903,0.0006720552,0.0003014254,0.0006379052,0.0007293959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003763509,"about_ca_system_score_gemma":0.0003603033,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005278597,"about_ca_topic_score_gemma":0.0003829335,"domain_scores_codex":[0.9997961,0.00001615327,0.00001425333,0.00005561731,0.00005968016,0.00005810639],"domain_scores_gemma":[0.9997848,0.00003672618,0.00006633663,0.00002414173,0.00003545496,0.0000526406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001129012,0.00001487656,0.0001470819,0.00005334471,0.000004364088,0.0001468178,0.000009630106,0.00004605663,0.9980611,0.0002494932,0.00008512819,0.001069099],"study_design_scores_gemma":[0.00004631827,0.0002467723,0.01439869,0.00001909561,0.00004814271,0.002932889,0.00004986524,0.002218849,0.9730998,0.0004998961,0.006418402,0.00002128929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9546018,0.01023845,0.02727599,0.0008948537,0.0006765489,0.0001091154,0.001172774,0.001116046,0.003914404],"genre_scores_gemma":[0.9878627,0.002606154,0.005681954,0.000200036,0.00006704022,0.00003745779,0.0006639239,0.00004256092,0.002838238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001217897,"threshold_uncertainty_score":0.004074275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04166719480111417,"score_gpt":0.323382096111931,"score_spread":0.2817149013108168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}