{"id":"W2014251969","doi":"10.1038/modpathol.2011.191","title":"Overexpression and oncogenic function of aldo-keto reductase family 1B10 (AKR1B10) in pancreatic carcinoma","year":2012,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Aldose Reductase and Taurine","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research","funders":"National Cancer Institute","keywords":"Carcinogenesis; Pancreatic cancer; KRAS; Cancer research; Biology; Adenocarcinoma; Immunohistochemistry; Pancreas; Apoptosis; Pathology; Cancer; Medicine; Endocrinology; Colorectal cancer; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000182402,0.0001504912,0.0002210872,0.00007137407,0.00003233384,0.00000325882,0.00006970832,0.0002071064,0.0000108317],"category_scores_gemma":[0.00003525281,0.0001397965,0.00005035557,0.00005837333,0.00009543441,0.000009390693,0.0001172806,0.00009644834,0.000004329247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001339242,"about_ca_system_score_gemma":0.00003798104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003585463,"about_ca_topic_score_gemma":0.000005772112,"domain_scores_codex":[0.998989,0.0001171576,0.0002334192,0.0002899235,0.00007696475,0.0002934894],"domain_scores_gemma":[0.9994678,0.00001119687,0.00009090466,0.0003159458,0.00002989793,0.00008422157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001946242,0.0001250145,0.03824275,0.00002980145,0.00001767178,0.00001123997,0.0001672092,0.000009164122,0.9578857,0.00006140819,0.0001799294,0.003075518],"study_design_scores_gemma":[0.002061842,0.0007667973,0.3245474,0.00004815677,0.0001010786,0.0003456149,0.0002687439,0.000206419,0.6681573,0.000920109,0.002178238,0.000398313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914023,0.007262423,0.0005784832,0.00002951334,0.0001181231,0.0001408592,0.00002521291,0.00000671755,0.0004363228],"genre_scores_gemma":[0.998737,0.0003209372,0.0003574991,0.0001159256,0.000174434,0.00002169087,0.0001304108,0.00002063499,0.0001215141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2897284,"threshold_uncertainty_score":0.5700735,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01265746576270509,"score_gpt":0.2387424070182239,"score_spread":0.2260849412555188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}