{"id":"W2014354522","doi":"10.1002/jcb.21832","title":"Association of Sp3 and estrogen receptor α with the transcriptionally active trefoil factor 1 promoter in MCF‐7 breast cancer cells","year":2008,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Cancer Institute; CancerCare Manitoba Foundation","keywords":"Estrogen receptor; RNA polymerase II; Molecular biology; Estrogen receptor beta; Promoter; Estrogen receptor alpha; Estrogen; Chromatin immunoprecipitation; Sp1 transcription factor; Cancer research; Transcription factor; Biology; Chemistry; Gene expression; Gene; Endocrinology; Cancer; Breast cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001320056,0.0001314548,0.0001762093,0.00003479627,0.00003858057,0.00000779908,0.0001139156,0.0001931148,0.00004636732],"category_scores_gemma":[0.00001103247,0.00009463481,0.00009456354,0.00009743156,0.00008215513,0.00001004855,0.00001528868,0.0001755008,2.860772e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000122285,"about_ca_system_score_gemma":0.0002743735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001679537,"about_ca_topic_score_gemma":0.0000160464,"domain_scores_codex":[0.9991088,0.00004477423,0.000283026,0.0001538995,0.0002720451,0.0001374844],"domain_scores_gemma":[0.9990835,0.00001086125,0.0004772413,0.0001202789,0.000251226,0.00005690989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004276955,0.00006410878,0.004061609,0.00003089372,0.0001780826,0.000002915099,0.0001612974,0.0001342128,0.9935219,2.689579e-7,0.0006235368,0.0007935116],"study_design_scores_gemma":[0.0009333679,0.0001144774,0.008462028,0.00005475041,0.00004761749,0.00008564842,0.00006952256,0.00001132392,0.9891948,0.000002226867,0.000917062,0.0001072256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973432,0.001285162,0.0001328574,0.0009420739,0.00006969857,0.00009130219,0.0001009562,0.000001518006,0.00003326503],"genre_scores_gemma":[0.9984312,0.0005302779,0.000142485,0.0000214497,0.0002930511,0.000004356956,0.00002425053,0.00001579602,0.0005371199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004400419,"threshold_uncertainty_score":0.3859095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00422974536651837,"score_gpt":0.1939560004402492,"score_spread":0.1897262550737308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}