{"id":"W2014354522","doi":"10.1002/jcb.21832","title":"Association of Sp3 and estrogen receptor α with the transcriptionally active trefoil factor 1 promoter in MCF‐7 breast cancer cells","year":2008,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Cancer Institute; CancerCare Manitoba Foundation","keywords":"Estrogen receptor; RNA polymerase II; Molecular biology; Estrogen receptor beta; Promoter; Estrogen receptor alpha; Estrogen; Chromatin immunoprecipitation; Sp1 transcription factor; Cancer research; Transcription factor; Biology; Chemistry; Gene expression; Gene; Endocrinology; Cancer; Breast cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001552202,0.0002186561,0.0002823141,0.000281836,0.0002397017,0.0002650283,0.0002276151,0.0002745292,0.001761747],"category_scores_gemma":[0.0001947099,0.0002325125,0.0003585103,0.0002221271,0.0001796924,0.000147965,0.0001840762,0.000592011,0.0008408741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003794527,"about_ca_system_score_gemma":0.0002034815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001975768,"about_ca_topic_score_gemma":0.002235014,"domain_scores_codex":[0.9997987,0.00002282897,0.000009590869,0.00004726048,0.00007335947,0.00004822672],"domain_scores_gemma":[0.9998626,0.00003464876,0.00002028993,0.00001904507,0.00003467008,0.00002882197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008007247,0.00001279836,0.0002681249,0.00002564005,0.000005252261,0.00004802788,0.00002062801,0.00002225857,0.9987084,0.00005577866,0.00004979766,0.0007031864],"study_design_scores_gemma":[0.00002323425,0.0001904167,0.02667757,0.00001550987,0.00001799971,0.0008166845,0.0001075356,0.001681154,0.9658017,0.0001025868,0.004555687,0.000009917942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982344,0.006217658,0.007184661,0.000287329,0.00008117057,0.00002783212,0.001106519,0.00009707834,0.002653744],"genre_scores_gemma":[0.9783682,0.001897709,0.00790392,0.0001812498,0.00003642954,0.00005894664,0.004015432,0.00003470559,0.007503543],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001975768,"threshold_uncertainty_score":0.005893588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00422974536651837,"score_gpt":0.1939560004402492,"score_spread":0.1897262550737308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}