{"id":"W2014409119","doi":"10.4161/cc.22136","title":"Ketone bodies and two-compartment tumor metabolism: Stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells","year":2012,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Diet and metabolism studies","field":"Medicine","cited_by":121,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Biology; Cancer cell; Ketone bodies; Cancer research; Stromal cell; Cancer; Tumor microenvironment; Metastasis; Mitochondrial biogenesis; Breast cancer; Mitochondrion; Cell biology; Biochemistry; Metabolism; Tumor cells","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001138342,0.0003035111,0.0002811138,0.0002075494,0.0001777641,0.0005587094,0.0001574312,0.0003085466,0.0006160089],"category_scores_gemma":[0.00009098936,0.0001104028,0.0002453339,0.0003135265,0.0002270971,0.0003811244,0.0002995889,0.0003463347,0.0002327625],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004100619,"about_ca_system_score_gemma":0.0002447891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00098946,"about_ca_topic_score_gemma":0.001901984,"domain_scores_codex":[0.9998792,0.00002064347,0.00001096235,0.00003444927,0.00003021051,0.0000245158],"domain_scores_gemma":[0.9999154,0.00001188781,0.00002745723,0.0000110168,0.00001277367,0.0000215815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002737394,0.00001517465,0.0009996651,0.000136934,0.00001185312,0.0001614016,0.00002760129,0.00009901175,0.9960084,0.0002414381,0.00004632328,0.001978439],"study_design_scores_gemma":[0.00001654189,0.0001926202,0.02055067,0.00001538313,0.00003049793,0.0009669441,0.0000943331,0.001450203,0.9719623,0.0003340045,0.00437456,0.00001192877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.962613,0.01849488,0.01453964,0.0005661664,0.00008586259,0.00004365666,0.00106307,0.0001402324,0.002453614],"genre_scores_gemma":[0.9911647,0.003485997,0.003086578,0.0001045562,0.00001512461,0.00002057172,0.0006482687,0.00001221685,0.001461888],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00098946,"threshold_uncertainty_score":0.002975225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01635534052045756,"score_gpt":0.2718328068336981,"score_spread":0.2554774663132405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}