{"id":"W2014424394","doi":"10.1203/01.pdr.0000181378.98593.3e","title":"Quantitative Acylcarnitine Profiling in Peripheral Blood Mononuclear Cells Using In Vitro Loading With Palmitic and 2-Oxoadipic Acids: Biochemical Confirmation of Fatty Acid Oxidation and Organic Acid Disorders","year":2005,"lang":"en","type":"article","venue":"Pediatric Research","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Federalno Ministarstvo Obrazovanja i Nauke; Bundesministerium für Bildung und Forschung; Universität Heidelberg","keywords":"Glutaric acid; Peripheral blood mononuclear cell; Palmitic acid; Medicine; Newborn screening; Propionic acidemia; Methylmalonic acid; Fatty acid; Beta oxidation; Biochemistry; Chemistry; In vitro; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005125048,0.0004880788,0.0004054198,0.0003044603,0.0004370644,0.000518343,0.000239635,0.0004599894,0.001174323],"category_scores_gemma":[0.0003399153,0.0001975371,0.0002118868,0.0005737547,0.0003457195,0.0002035329,0.0002722654,0.0007260519,0.0007780864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001679054,"about_ca_system_score_gemma":0.0002313297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008698878,"about_ca_topic_score_gemma":0.001707677,"domain_scores_codex":[0.999325,0.0002483024,0.00006500573,0.0001264538,0.0001201655,0.000115022],"domain_scores_gemma":[0.9997489,0.00007418173,0.00002199976,0.00006297464,0.00005567475,0.0000361931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003165176,0.00003064895,0.0003290556,0.00001491241,0.000004082969,0.00002773891,0.00002796122,0.00001803591,0.998534,0.00001989143,0.00001927991,0.0006579268],"study_design_scores_gemma":[0.00003828931,0.0004161485,0.007642743,0.000004003159,0.00003467309,0.000201817,0.00006708497,0.0006046841,0.9901799,0.00005398336,0.0007517489,0.0000049773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9571195,0.002172902,0.03488825,0.0002676284,0.000195074,0.0002533398,0.002049441,0.0001591081,0.002894613],"genre_scores_gemma":[0.9640532,0.001280713,0.02684903,0.0002352373,0.0001036668,0.0003564944,0.002752182,0.00006935131,0.004300158],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001174323,"threshold_uncertainty_score":0.003928542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01957957323993817,"score_gpt":0.2989096467583711,"score_spread":0.2793300735184329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}