{"id":"W2014435766","doi":"10.1002/(sici)1097-4652(200001)182:1<33::aid-jcp4>3.0.co;2-5","title":"Human thioredoxin attenuates hypoxia-reoxygenation injury of murine endothelial cells in a thiol-free condition","year":2000,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"Medical Research Council","keywords":"Thiol; Thioredoxin; Glutathione; Chemistry; Intracellular; Hypoxia (environmental); Cell biology; Biochemistry; Molecular biology; Biology; Oxidative stress; Enzyme; Oxygen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003071396,0.000166051,0.0003654949,0.0001288303,0.00004447435,0.00000439997,0.0003569075,0.0002624392,0.0002264052],"category_scores_gemma":[0.00005216389,0.0001392331,0.0001737689,0.00009033782,0.0002197073,0.00001292251,0.00005924871,0.0002307218,0.000008762157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001450689,"about_ca_system_score_gemma":0.00005344646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001379686,"about_ca_topic_score_gemma":0.00001015491,"domain_scores_codex":[0.9985658,0.0003081071,0.0005917609,0.0002084076,0.0001142667,0.0002116387],"domain_scores_gemma":[0.9990488,0.00002562229,0.0004478659,0.0002762625,0.0001521492,0.00004935748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004725693,0.0002114524,0.0002234335,0.0000202114,0.00007378187,0.00001011778,0.00005591997,0.0001742681,0.9969651,0.0000989734,0.0008400379,0.0008541116],"study_design_scores_gemma":[0.00137212,0.001366303,0.01354965,0.00003034502,0.00002058751,0.00001768134,0.00003982936,0.00001096305,0.9785362,0.002165364,0.002759474,0.0001314631],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985897,0.0003288043,0.00006577714,0.00008625571,0.0001779978,0.0001100119,0.00007204589,0.000002756988,0.0005666764],"genre_scores_gemma":[0.9985005,0.000337348,0.0001883196,0.0001126809,0.0004374133,0.000003836933,0.0000980176,0.00001408307,0.0003078081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0184289,"threshold_uncertainty_score":0.5677763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005450056615887874,"score_gpt":0.2442729737564412,"score_spread":0.2388229171405533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}